The Resource technologist C will provide high quality cell sorting and analytical services to the investigators using the Penn Cytomics and Cell Sorting Shared Resource Laboratory. Working closely with the Technical Director in the development of quality assurance protocols for a wide variety of instrumentation, the successful candidate will also be responsible for performing and documenting the daily quality assurance of cytometry instrumentation across multiple departments. Knowledge of complex flow cytometry instrumentation is required, with minimum of 3-5 years of analytical flow cytometry or cell sorter experience. Experience with BD Biosciences platforms preferred but other platforms considered for the experienced candidate. Knowledge of biosafety practices and procedures is required for the C position. This position involves working closely with a wide array of investigators from multiple departments across campus and implementing best practices for analysis and cell sorting. Additional duties include developing and updating standard operating procedures, participating in equipment or protocol validation, and for the C position, training qualified users for independent cell sorting and analysis. Participation in continuing education in cytometry is expected. The professional cytometry certification, SCYM(ASCP)CM is a plus, but support to obtain this qualification will be provided for the successful candidate. This role focuses on quality control method development, execution and analysis, method validation and method transfers, reagent evaluation and characterization for compliance testing, including sourcing and development of comparability testing protocols for alternative sources and secondary suppliers. Will design, coordinate and perform reagent qualification and maintenance programs, monitor frequency of testing and resource availability, and track trend data and report results. The individual will support analytical method validation and stability programs by writing validation protocols incorporating solid study design with appropriate acceptance criteria, conducting qualification and/or validation experiments, analyze data, and prepare scientific information reports.