Research Technologist-KirschnerChandra -Limited Tenure Hematology Research

Mayo Clinic • Rochester, MN

99d

About The Position

Sets up and performs routine and established lab procedures in support of lab goals, grant commitments, i.e. assays, cell/tissue culture, animal studies, etc. Monitors results, reports unusual outcomes and suggests modifications. Collects, enters and summarizes data. Assists in the maintenance of lab equipment and supplies. Performs basic statistical data analysis; prepares tables/charts/graphs and assists in organizing data. Presents at research laboratory meetings and contributes to writing of manuscripts. Works under supervision and may perform some assignments independently as discussed and approved by Principal Investigator. The current project is to bioinformatically investigate the molecular evolution of clonal hematopoiesis in breast cancer and link this information to the rich outcomes in clinical cohorts at the Mayo Clinic. The job requires bioinformatic, database, web authoring and programming skills for this 2-year project. The overall objective is to accurately call somatic mutations in large cohorts based on our previously published LiFT filter and to link cancer progression and outcome data to mutation status. The position will drive data integration approaches from different sources such as whole genome sequencing, single cell omics, bulk RNA-seq and ATAC-Seq and DNA and develop analysis pipelines. The post-holder will establish new bioinformatics data analysis methods as required and communicate developments in the field of genomics and hematology to the local research community. The post-holder will be responsible for management of good data storage practices, adherence to relevant regulation (for example human data), methods development, SOPs, budget management and appropriate record keeping. The post-holder provide in-depth bioinformatics-based technical support to members of the Kirschner lab.

Requirements

• Bachelor's degree in biology, chemistry, or other relevant science, or an associate's degree with 6 years of relevant laboratory experience.
• Solid understanding of lab techniques, equipment, and safety.
• Ability to organize and carry out laboratory techniques independently and in a team setting.
• Experience with basic data analysis.
• Demonstrated writing skills.

Responsibilities

• Sets up and performs routine and established lab procedures in support of lab goals and grant commitments.
• Monitors results, reports unusual outcomes and suggests modifications.
• Collects, enters and summarizes data.
• Assists in the maintenance of lab equipment and supplies.
• Performs basic statistical data analysis; prepares tables/charts/graphs and assists in organizing data.
• Presents at research laboratory meetings and contributes to writing of manuscripts.
• Works under supervision and may perform some assignments independently as discussed and approved by Principal Investigator.
• Investigates the molecular evolution of clonal hematopoiesis in breast cancer.
• Links information to clinical outcomes at the Mayo Clinic.
• Drives data integration approaches from different sources such as whole genome sequencing, single cell omics, bulk RNA-seq and ATAC-Seq.
• Develops analysis pipelines.
• Establishes new bioinformatics data analysis methods as required.
• Communicates developments in the field of genomics and hematology to the local research community.
• Manages good data storage practices and adheres to relevant regulations.
• Develops methods, SOPs, and manages budgets.
• Provides in-depth bioinformatics-based technical support to members of the Kirschner lab.

What This Job Offers

• Industry: Hospitals
• Education Level: Bachelor's degree