Research Technologist – Analytical Development and Quality Control (GMP)

Roswell Park Comprehensive Cancer Center

3d • Onsite

About The Position

Join a mission-driven team at the forefront of cutting-edge cell and gene therapies. At Roswell Park’s state-of-the-art GMP Engineering & Cell Manufacturing (GEM) Facility, we are pioneering advanced immunotherapies like CAR-T with the goal of transforming patient care. We are seeking a Research Technologist to play a key role in Analytical Development and Quality Control for the release testing of cell therapy products. This is a hands-on, lab-based position within a dynamic cGMP environment, ideally suited for individuals passionate about cellular therapeutics and high-impact translational research.

Requirements

• Master’s degree in a clinical or scientific discipline; or
• Bachelor’s degree in a clinical or scientific discipline and the equivalent of one (1) year of full-time experience in a laboratory setting.
• A strong foundation in cell culture and aseptic technique, ideally in a cGMP or regulated environment.
• A detail-oriented mindset with a commitment to quality and operational excellence.
• Effective communication and teamwork skills to support cross-departmental projects.
• Adaptability and drive to work in a fast-paced, evolving field at the intersection of science and medicine.
• Strong interpersonal skills and the ability to communicate clearly across functions and teams.
• Highly organized with the ability to manage multiple tasks and meet tight deadlines.
• Excellent verbal and written communication skills.
• Resourceful and solutions-focused mindset with a strong sense of ownership.
• Adaptable and resilient in a fast-paced, mission-critical setting.

Nice To Haves

• Extensive experience in Analytical Development or Quality Control settings
• Demonstrated proficiency in cellular and molecular assays, such as flow cytometry, cytotoxicity, qPCR, dPCR, ELISA, and a strong analytical mindset and troubleshooting capabilities.
• Working knowledge of cGMP standards, FDA/EU/ICH guidelines related to manufacturing of cell-based products is strongly preferred.
• Solid foundation in aseptic technique and mammalian cell culture, with a track record of maintaining sterility and culture integrity in high-throughput or regulated settings.
• Strong communication skills, with the ability to convey scientific concepts clearly across cross-functional teams; collaborative, articulate, and committed to scientific excellence.
• Hands-on experience in cell therapy such as CAR-T, stem cell-based platforms, or other adaptive cell transfer modalities spanning research, process development, or manufacturing.
• Exceptional attention to detail, especially in documentation, cleanliness, and organization critical qualities for maintaining reproducibility and regulatory compliance.

Responsibilities

• Execute analytical development and QC release testing of cell and gene therapy products under cGMP conditions, including endotoxin, sterility, qPCR, dPCR and potency assays.
• Draft, Review and maintain Standard Operating Procedure (SOPs), worksheets, forms, and QC release reports.
• Set up, calibrate and maintain QC instruments, perform Preventative Maintenance, and/or conduction of IQ/OQ/PQ.
• Ensure compliance with GMP/FDA guidelines and regulatory requirements for product release
• Collaborate cross-functionally with Manufacturing Sciences, Process Development, Vector Development, and Quality Assurance teams to ensure seamless technology transfer, method suitability and qualification studies.
• Contribute to continuous improvement initiatives to optimize processes and ensure readiness for clinical trial demands and regulatory audits.

Benefits

• Be part of a nationally recognized cancer center with a legacy of innovation and patient-centered care.
• Access to world-class facilities, resources, and training to support your professional growth.
• The opportunity to directly contribute to life-saving therapies that make a difference in patients’ lives.
• The compensation range for this position is $52,979 - 67,185 and this includes a full comprehensive benefits package.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Number of Employees: 501-1,000 employees