Research Technician III

Children’s Hospital of Philadelphia•Philadelphia, PA

About The Position

This role participates in planned research projects by performing research protocols with minimal direction and guidance from the principal investigator, program director or senior scientists. May exercise moderate discretion and judgment in the execution and interpretation of experiments, and of data derived. The Lefebvre research team seeks to better understand the genetic mechanisms that control the healthy development of the skeleton and brain and that are disrupted in specific skeletal malformation and neurodevelopmental disorders and leverages new information to develop novel strategies to treat these disorders. The team uses multipronged approaches, including cutting-edge and high-throughput assays, iPSC-derived organoids, animal models and in silico approaches. We are looking for a research technician to take on a lab manager role as well as to carry out experimental work and analyze data alongside trainees and scientists. The ideal candidate will have solid experience in lab management and wet lab research, proficiency in mouse husbandry, histology, cell culture and molecular biology techniques, and excellent written and oral communication skills.

Requirements

At least two (2) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Required
Advanced understanding of lab procedures, protocols, and equipment.
Intermediate proficiency with lab specific experiments / techniques.
Intermediate scientific analysis skills.
Excellent verbal and written communications skills
Excellent organizational skills
Strong critical thinking / problem-solving skills
Strong analytical skills
High School Diploma / GED Required

Nice To Haves

Bachelor's Degree with a major in Biology, Genetics or a closely related discipline Preferred
Master of Science Degree Preferred
At least two (2) years of laboratory research experience Preferred
At least three (3) years of related classroom experience or successful completion of a technical training program (eg. Wistar, WPSI) and research laboratory experience Preferred

Responsibilities

Performs research procedures on experimental samples with minimal supervision
Formulates and performs complex lab experiments and analyzes/ reports the data
Performs tasks that require knowledge of advanced techniques and lab equipment
Performs advanced calculations and maintains appropriate log and lab notebooks
Assists with planning specific research protocols and procedures
Assists in development & troubleshooting of new techniques and ideas
May be required to modify scientific methods and protocols (in conjunction with PI)
Checks others' results for completeness and accuracy
May be responsible for training and mentoring new staff
May assist in the preparation of grants journal articles, posters and oral presentations
May perform routine and non-routine tests / experiments as needed
Maintains office, lab area, reagents, supplies and equipment
Performs routine maintenance on lab equipment
Coordinates schedules of tests & procedures
Attends courses, seminars, and lab meetings to expand knowledge of research and laboratory techniques
Records results, organizes data and maintains lab notebook in an organized manner
Conducts literary searches as required