The Tufts Department of Biology has diverse research interests and is engaged in cutting-edge biological research in molecular biology, genetics, cell biology, neurobiology, physiology, plant ecology, animal behavior, and conservation biology. The Department of Biology maintains an active research and teaching program on the Medford campus and in various field locales, and trains and advises graduate and undergraduate students as well as post-doctoral fellows. This is a one-year limited term position. The laboratory of Dr. Sarah R. Hengel studies the intersection of repair proteins involved in DNA lesion recognition and homologous recombination. The lab is specifically focused on uncovering the underlying mechanisms of how DNA damage caused by environmental toxicants in DNA structures is recognized by the human Shu complex and repaired by either RAD51-dependent or RAD52-dependent damage repair mechanisms. The lab combines cell biology, biochemistry, biophysics, and single-molecule tweezers (C-trap) approaches to uncover novel insights into the mechanisms of DNA repair in aging, disease, and cancer. The research technician will order reagents for the laboratory, purify recombinant protein, perform FRET-based biophysical assays, perform EMSA analysis, record and analyze data, and meet with Dr. Hengel about data. Conducts routine experiments following appropriate protocols and procedures to achieve results. Performs limited data interpretation and assists with basic statistics and analysis Meet with supervisor each week to discuss data analysis and scientific conclusions Records results and maintains accurate records of experiments Maintains laboratory equipment and orders/keeps inventory of supplies Prepares stock solutions, reagents and other media
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Job Type
Full-time
Career Level
Entry Level