Research Specialist (DOM Infectious Disease)

Johns Hopkins University•Baltimore, MD

8d•$17 - $30•Onsite

About The Position

We are seeking a Research Specialist with an understanding of, and demonstrated skills in, techniques involved in in vitro and highly specialized in vivo (in particular, murine) models of mycobacterial infection and the evaluation of drug efficacy. The individual will rely on knowledge and experience to assist in the planning and conduct of a pre-clinical research program in antibiotic development for treatment of tuberculosis and infections with other mycobacteria. Under general supervision, the individual will be assigned projects for stepwise assessment of the activity of new drugs in vitro and in mouse models and will be responsible for developing protocols for PI approval. The Research Specialist performs a range of assays and experiments specific to an area of research, requiring a good understanding of the work of the laboratory. Makes contributions various aspects of research efforts. Perform routine troubleshooting and help with training and orientation of others working in the laboratory.

Requirements

Bachelor's Degree in Biology, Chemistry or related field.
One year of laboratory experience performing relevant techniques.
Additional education may substitute for required experience and additional related experience may substitute for required education permitted by the JHU equivalency formula beyond a high school diploma/ graduation equivalent, to the extent permitted by the JHU equivalency formula.

Responsibilities

Plan and run experiments after discussion with investigators. Work may include making protocol modifications within the parameters set by investigator.
Utilize specialized knowledge to interpret results, e.g. read controls, and evaluate results.
Use scientific knowledge and lab experience to evaluate whether component parts of experiments are working as expected.
Train/orient learners and new staff in the laboratory.
Assist in development of new techniques and instruments.
Become familiar with published research methods related to current experimental work by investigating published protocols and discussing them with more senior laboratory staff and/or faculty investigators.
Process analyzed data into figures for scientific publications.
May order equipment and supplies, and interface with vendors.
May facilitate problem solving for entry-level lab members with research assays.
May participate in protocol development, efficiency, and productivity.
May contribute to writing manuscripts and grants by writing methodology sections.
Other duties as assigned.
Follow established procedures and utilize aseptic technique to perform in vitro experiments to assess antimicrobial activity and molecular readouts.
Coordinate, supervise and actively participate in conduct of in vitro and animal experiments to evaluate new drug candidates and resistant mutants.
Cultivate pathogenic bacteria, including Mycobacterium tuberculosis.
Handle bio-hazardous material under Biosafety Level 2 and Biosafety Level 3 conditions without supervision.
Infect animals through the aerosol route without supervision.
Administer antibiotics or other anti-infectives to animals using injection or oral gavage without supervision.