Research Specialist; Biochemistry (Schey Lab)

Vanderbilt University • Nashville, TN

417d

About The Position

The Research Specialist in the Schey Lab at Vanderbilt University focuses on executing proteomic workflows using advanced mass spectrometry techniques. This role involves sample preparation, data acquisition, and analysis, as well as the development of assays for brain protein modifications. The position supports the mission of the Mass Spectrometry Research Center by providing expertise in proteomics and contributing to NIH- and ARPA-H funded projects.

Requirements

• MS in physical or biological sciences is required
• At least two years of post-graduate experience required, five years of experience is preferred
• Laboratory experience in proteomics, biochemistry, or analytical chemistry
• Experience in protein/peptide analysis using HPLC - tandem mass spectrometry (LC-MS/MS)
• Mass spectrometry data analysis is desired
• Strong organizational skills
• Strong written and verbal communication skills
• Ability to learn and assist in development of new protocols in an evolving field

Responsibilities

• Execution of proteomic LC-MS/MS workflows
• Follow specific workflows for sample preparation of human brain protein samples, including protein enrichment/purification, protein digestion, and sample clean-up
• LC-MS/MS instrument operation and acquisition of proteomic data
• Data analysis of proteomic data
• Develop ELISA assays for specific brain protein modifications
• Run neurotoxicity assays
• Daily operation and routine maintenance of LC-MS/MS instrumentation
• Operation of instrument software for instrument calibration and data acquisition
• Performance of instrument QA/QC procedures
• Routine laboratory maintenance
• Supply ordering
• Data management
• Record-keeping
• Chemical waste disposal

What This Job Offers

• Job Type: Full-time
• Industry: Educational Services
• Education Level: Master's degree