(Senior) Research Scientist - DNA Assembly & NGS Integration

Genscript Biotech Corp•Redmond, WA

62d•$90,000 - $120,000•Onsite

About The Position

GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy. GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology. ProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy, vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio's total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. GenScript is seeking a highly motivated and scientifically rigorous (Senior) Research Scientist with deep expertise in molecular biology, synthetic DNA assembly, and next-generation sequencing (NGS). This role will drive development of innovative, high-fidelity DNA products-leveraging advanced cloning, cell-free amplification, and NGS analytics to accelerate synthetic biology R&D and product development. The successful candidate will combine experimental precision with strong analytical and problem-solving skills in a collaborative, fast-paced environment.

Requirements

Ph.D. in Molecular Biology, Synthetic Biology, Biochemistry, Genomics, or related discipline, with ≥ 2 years of post-doctoral or industry experience in DNA-based R&D.
Proven hands-on expertise in DNA assembly technologies (e.g., Gibson, Golden Gate, ligation-free, or cell-free cloning systems).
Demonstrated proficiency with NGS workflows-library preparation, target enrichment, QC, and data interpretation for construct validation.
Familiarity with bioinformatics tools for read mapping, variant calling, and error-rate analysis.
Strong analytical, quantitative, and problem-solving skills, with ability to interpret complex sequencing and assembly data.
Excellent communication and interpersonal skills; effective collaborator across interdisciplinary scientific and operational teams.
Highly organized with demonstrated ability to manage multiple concurrent projects under dynamic timelines.
A growth-oriented mindset-curious, collaborative, and committed to technical and personal excellence.
Ability to lift up to 15 lbs as required.

Responsibilities

Lead R&D initiatives in DNA synthesis, assembly, and quality control, integrating molecular engineering with high-throughput sequencing and bioinformatics workflows.
Design and construct complex DNA assemblies (multi-fragment, scar-free, or modular systems) using Gibson, Golden Gate, or cell-free assembly methods.
Implement NGS-based verification and error-profiling pipelines to evaluate construct accuracy, coverage, and sequence fidelity.
Develop and optimize analytical and preparative workflows-including amplification, purification, and quantification of synthetic DNA products.
Collaborate with cross-functional teams (bioinformatics, process development, and manufacturing) to translate R&D innovations into scalable, production-ready methods.
Interpret large, complex datasets; perform statistical analyses; and present findings with clarity and actionable recommendations.
Manage project timelines, deliverables, and documentation in accordance with internal SOPs and quality standards.
Proactively identify technical challenges, propose creative solutions, and mentor team members on experimental design and troubleshooting.
Maintain detailed laboratory notebooks, ensure equipment readiness, and contribute to a culture of operational excellence and scientific integrity.