Research Scientist Engineer 4

University of Washington Medical Center•Seattle, WA

10d

About The Position

The Department of Anesthesiology & Pain Medicine has an outstanding opportunity for a Research Scientist/Engineer 4 to join their team. The Raftery research group focuses on developing new methods and applications of metabolite profiling using a combination of mass spectrometry (MS) and NMR platforms which provide a broad-based approach for biomarker discovery and systems biology research. The main purpose of this position is to analyze the metabolomics data that we generate, as well as complementary, available genomic or proteomic data for several projects focused on understanding the biology of aging. The aging studies focus on numerous organisms, including humans, dogs, flies and through the Nathan Shock Center, mice or other model organisms. The Department of Anesthesiology & Pain Medicine has an outstanding opportunity for a Research Scientist/Engineer 4 to join the Raftery lab to investigate the biology of aging using metabolomics, genomics, and systems biology. This position is at 100% FTE. The RSE4 will need a high level of skill in oral and written scientific communication and extensive knowledge of systems biology, statistics and computational methods. The position will focus primarily on the statistical and pathway analysis of the complex metabolite data, including generating creative and new methods of analysis of the data, but will also involve biological interpretation and assisting other researchers with study design. The Scientist will be responsible for generating draft manuscripts and in assisting with proposal writing.

Requirements

Master’s degree in Genetics or Biochemistry and four years of relevant experience
Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.
This position requires extensive systems biology, statistics, and computational methods knowledge as well as knowledge in the biology of aging.
A high level of skill in oral and written scientific communication, including presenting at national and international conferences, and authorship and co-authorship of publications and grants.
Extensive knowledge of statistical methods including multivariate and univariate analysis of large data sets, learning and predictive modeling, network analysis, and probabilistic approaches to test theories and develop hypotheses in systems biology.
Systems biology knowledge requires a foundation in biology ranging from a detailed understanding of genetics, biochemistry, and molecular biology to whole organism physiology, development, and population demography. Those elements are utilized in developing and testing theories of aging and other biological phenomena using high-dimensional metabolomics, genomics, knowledge-based networks, and other data type.

Nice To Haves

This position is best served by someone who can work independently to facilitate collaboration between investigators working across different fields of aging, biology and chemistry.
A fundamental understanding of mass spectrometry and chemical analysis is highly desired as it greatly increases the breadth of collaborations with the UW Northwest Metabolomics Research Center.

Responsibilities

Consult and coordinate on research efforts and study design with collaborators focused on aging.
Write, develop, and modify data analysis code and workflows.
Perform data transfer, data preparation, and cleanup of high-dimensional experimental data.
Perform advanced statistical analysis of high-dimensional experimental data.
Interpret findings within the biological context.
Contribute experimental hypotheses for new scientific inquiries and novel directions of research.
Assist researchers associated with the Shock Center pilot program by providing scientific feedback to enhance their research objectives.
Participate in and contribute to scientific meetings of the Nathan Shock Center.
Prepare analytic results for reports, publications, and presentations
Initiate and/or contribute to the scientific writing of peer-reviewed publications.
Contribute to scientific writing for grant applications.
Communicate with collaborators and the larger scientific community via research presentations.