Research Postdoctoral Fellow - Molecular and Cellular Biologist

Mayo Clinic • Rochester, MN

5d

About The Position

The Wyles lab in the Mayo Clinic Department of Dermatology is seeking a highly motivated postdoctoral fellow to study the association between cutting-edge biomarkers of skin health span and tissue engineering. In this role, the candidate will lead independent projects focused on defining the molecular and cellular mechanisms of skin senescence using advanced human skin models, with relevance to aging, regeneration, and longevity biology. The successful candidate will bring strong PhD-level training in molecular and cellular biology and will work at the interface of wet-lab experimentation and multi-omic data interpretation in a highly collaborative, interdisciplinary environment. This position offers the opportunity to lead innovative, translational research at the intersection of dermatology, regenerative medicine, and aging biology within a well-resourced academic medical center.
A Research Fellow position in Life Sciences (LS) will require knowledge of either clinical-based research or laboratory-based research often obtained from a postdoctoral program.
"A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Upon background check and CCATS Executive Committee approval, Research Fellow may have patient/research subject contact directly relating to and incidental to the original research program. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic."

Requirements

• Strong PhD-level training in molecular and cellular biology
• Molecular and cellular biology techniques, including PCR/qPCR and molecular assays
• Primary and immortalized skin cell culture, including keratinocytes, melanocytes, and fibroblasts
• Histopathology, immunohistochemistry, immunofluorescence, and advanced staining techniques
• Quantitative image analysis and data interpretation
• Molecular and cellular analyses related to aging, senescence, and tissue regeneration
• 3D skin equivalents, explants, organotypic cultures, or other in vitro human skin models
• Omics-based approaches (e.g., transcriptomics, proteomics, spatial or multi-omics) and integration of molecular datasets
• Rigorous experimental design, data analysis, and scientific reproducibility
• Excellent manuscript writing, presentation, and scientific communication skills

Nice To Haves

• Computational or bioinformatic analysis of biological data

Responsibilities

• Lead independent projects focused on defining the molecular and cellular mechanisms of skin senescence using advanced human skin models
• Work at the interface of wet-lab experimentation and multi-omic data interpretation in a highly collaborative, interdisciplinary environment

Benefits

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree