UNIV - Research Laboratory Manager - Department of Radiation Medicine

Medical University of South CarolinaCharleston, SC
5d

About The Position

The Laboratory Manager is responsible for the daily operational oversight of the laboratory, ensuring efficient execution of research activities and maintaining high standards of scientific rigor, quality control, and regulatory compliance. This individual provides direct supervision of laboratory personnel and coordinates day-to-day functions to support the Principal Investigator’s research program. Directs large, complex research projects in a clinical or research setting, ensuring all laboratory staff follow and adhere to safety and all applicable health policies and regulations The Laboratory Manager plays a central role in ensuring operational excellence, scientific productivity, and effective collaboration across the department, school, and external partners.

Requirements

  • Bachelor of Science degree in medical technology, microbiology, biochemistry or a closely related field and relevant experience in a clinical or research laboratory environment.
  • Minimum of 5 years of relevant laboratory experience, preferably in an academic, translational, or biotechnology setting
  • Demonstrated experience with next-generation sequencing (NGS), digital droplet PCR (ddPCR), liquid handling/automation platforms, and related molecular assay development preferred
  • Strong organizational, project management, and supervisory skills
  • Experience maintaining regulatory compliance and quality control standards
  • Bachelor of Science degree in medical technology, microbiology, biochemistry or a closely related field and four years’ relevant experience in a clinical or research laboratory environment; relevant experience includes minimum of one year of experience supervising or managing a research laboratory.
  • Ability to perform job functions in an upright position.
  • Ability to perform job functions in a seated position.
  • Ability to perform job functions while walking/mobile.
  • Ability to climb, using step stool.
  • Ability to work in temperature extremes (32° F to 100° F) when required due to assignments in cold rooms and/or foreign countries.
  • Ability to work in confined/cramped spaces.
  • Ability to bend at the waist.
  • Ability to twist at the waist.
  • Ability to fully use both hands/arms.
  • Ability to perform repetitive motions with hands/wrists/elbows and shoulders.
  • Ability to fully use both legs.
  • Ability to reach in all directions, stretch, bend, while moving items/materials from both sitting and standing positions.
  • Ability to maintain good olfactory sensory function/distinction.
  • Ability to lift materials up to 20 lbs., unassisted.
  • Ability to lift and carry 4 liter waste material bottles a distance of 30 feet, unassisted.
  • Ability to lift and carry 25-30 lbs. jugs of liquid a distance of 100 feet, unassisted.
  • Ability to lift file boxes, from floor level to counter tops, unassisted.
  • Ability to push/
  • Ability to lift 40 lbs. centrifuge rotors from floor level to height of 40 inches, then down 20 inches into centrifuge drum, unassisted.
  • Ability to lift 25 lbs. boxes, from floor level to maximum height of 72 inches, unassisted.
  • Ability to push/pull file boxes from one location to another at floor level.
  • Ability to maneuver heavy equipment on bench tops, 50 lbs. or greater, unassisted.
  • Ability to perform gross motor functions with frequent fine motor movements.
  • Ability to maintain 20/40 vision, corrected, in one eye or with both eyes.
  • Ability to match or discriminate between colors, normally.
  • Ability to hear and recognize various alarms emitting from work area systems.
  • Ability to hear and/or understand conversations.
  • Ability to work in a darkroom for processing film, etc.
  • Ability to be qualified physically for respirator use, initially and annually.
  • Ability to work rotating shifts as required.
  • Ability to work overtime as required.
  • Ability to learn and use new processes, tools and equipment as required.

Responsibilities

  • Personnel and Lab Operations Management: Oversee daily laboratory operations and supervise laboratory staff. Ensure proper planning, coordination, and execution of experiments across multiple projects. Assist in onboarding and training of laboratory personnel. Conducts annual and intermittent performance reviews of supervised research staff in accordance with MUSC Human Resources Policies and Procedures.
  • Purchasing and Inventory Management: Manage research inventory, ordering, and stocking of supplies and reagents. Maintain and troubleshoot laboratory equipment; coordinate servicing, calibration, and preventive maintenance. Works with Finance Manager for AIMS inventory reporting related to existing and new research equipment.
  • Research Design and Collaboration: Design and conduct experiments for research projects. Conduct comprehensive analysis of ddpcr and NGS data and interpret results. Ensure compliance with institutional, biosafety, chemical safety, and regulatory requirements. Coordinate activities with institutional core facilities, clinical teams, and external collaborators.
  • Regulatory and Compliance Management: Develop, implement, and maintain laboratory standard operating procedures (SOPs) and quality systems. Support assay development, optimization, validation, and documentation. Monitors all lab personnel to ensure adherence to safety and health policies and regulations, as well as federal and state mandates and accepted scientific practices. Follows IRB, human subjects, ACUC, and other State, Institutional and Federal regulatory protocols, as needed.
  • Special Projects: Prepares periodic and special narrative and statistical reports to advise principal investigators and others on research techniques and procedures. Oversees and performs examination and testing for clinical and basic sciences research purposes. Assists with grant and research proposal submissions. Plans and organizes research and evaluation of scientific literature; composes and reviews articles for publication in scientific journals. Uses manual and computer techniques to analyze research data.
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