Research Lab Tech II
About The Position
The Department of Pathology and Laboratory Medicine, located at USC Keck School of Medicine, is seeking a full-time Research Laboratory Technician II to join our research team of highly skilled senior research associates, technicians, and faculty researchers. Under the direction of Principal Investigators, our research studies focus on peptidic effectors of mammalian innate immunity for drug development. The laboratory employs an array of general scientific laboratory research practices and procedures, including molecular biology, protein biochemistry, enzyme kinetics, immune signaling pathways, microbiology, and animal models for acute and chronic inflammatory diseases. Under direct supervision, he/she will be performing in vitro (cell culture) and in vivo (rodent) experiments to evaluate physiologic and molecular effects and mechanisms of peptidic agents. He/she will be testing a library of synthetic peptides for their immunomodulatory properties in infection and inflammatory disease models. The Research Lab Technician II will administer peptide treatment while collecting data for clinical/in-life presentation of disease (i.e., survivability, weight gain/loss, disease severity, mortality, and/or morbidity), post-mortem indicators of disease (i.e., bacterial or fungal burden). He/she will be responsible for obtaining, maintaining, and graphing of data. The technician will inoculate rodents with pathogens by intraperitoneal or intravenous injections, and he/she will give drug treatment or placebos to infected animals, harvest organs for histochemical analysis, collect blood for pharmacokinetics, and enumerate bacterial/fungal load as a function of peptide treatment. In our inflammatory disease models, maintaining a rodent colony, measuring weights, and recording visual observations may be employed. Additional pharmacokinetics will be analyzed utilizing uninfected rabbits as a secondary model. The candidate is required to complete animal tutorial training and receive certification in general laboratory safety before any work is performed in the laboratory. The University offers a competitive salary and benefit package This is a grant-funded position Flexible hours will be required.
Requirements
- Minimum Education: Associate's degree, Specialized/technical training, Combined experience/education as substitute for minimum education
- Minimum Experience: 2 years
- Minimum Field of Expertise: Working knowledge of laboratory equipment and research protocols. Knowledge of computer analysis techniques and ability to provide routine analysis and interpretation of research data.
- The candidate is required to complete animal tutorial training and receive certification in general laboratory safety before any work is performed in the laboratory.
Nice To Haves
- Highly Preferred Experience :Previous general scientific laboratory research practices and rodent animal handling are required for this position
Responsibilities
- Performing in vitro (cell culture) and in vivo (rodent) experiments to evaluate physiologic and molecular effects and mechanisms of peptidic agents.
- Testing a library of synthetic peptides for their immunomodulatory properties in infection and inflammatory disease models.
- Administer peptide treatment while collecting data for clinical/in-life presentation of disease (i.e., survivability, weight gain/loss, disease severity, mortality, and/or morbidity), post-mortem indicators of disease (i.e., bacterial or fungal burden).
- Obtaining, maintaining, and graphing of data.
- Inoculating rodents with pathogens by intraperitoneal or intravenous injections, and he/she will give drug treatment or placebos to infected animals, harvest organs for histochemical analysis, collect blood for pharmacokinetics, and enumerate bacterial/fungal load as a function of peptide treatment.
- Maintaining a rodent colony, measuring weights, and recording visual observations may be employed.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Associate degree
