Research Fellow-PC-Nephrology-Chebib Lab

Mayo Clinic • Jacksonville, FL

3d

About The Position

The Chebib PKD Research and Therapeutics Laboratory in the Division of
Nephrology and Hypertension at Mayo Clinic Florida is seeking a highly motivated
Postdoctoral Research Fellow to join a multidisciplinary program focused on the
development of novel therapies for genetic kidney diseases, with particular
emphasis on autosomal dominant polycystic kidney disease.

The laboratory integrates molecular biology, gene therapy, and translational
disease models to identify and advance therapeutic strategies targeting
fundamental mechanisms of cystogenesis and kidney injury.

The successful candidate will contribute to projects centered on gene delivery
platforms, including adeno-associated virus and lipid nanoparticle systems, with
the goal of developing next generation therapeutic approaches for monogenic
kidney diseases.
The fellow will design and conduct experimental studies involving vector
engineering, nucleic acid delivery, and mechanistic evaluation of gene and
RNA-based therapies in cellular and preclinical models.

Responsibilities will include molecular cloning, vector production and
characterization, evaluation of transgene expression and pathway modulation, and
integration of functional assays relevant to kidney epithelial biology.

The position offers opportunities to collaborate with investigators across Mayo
Clinic in areas including gene therapy, regenerative medicine, metabolomics, and
advanced imaging, and to contribute to projects that bridge mechanistic
discovery with translational therapeutic development. It also provides access to
state of the art research infrastructure and the opportunity to contribute to
innovative programs
aimed at advancing therapies for inherited kidney diseases.

A Research Fellow position in Life Sciences (LS) will require knowledge of
either clinical-based research or laboratory-based research often obtained from
a postdoctoral program.

A Research Fellow at Mayo Clinic is a temporary position intended to provide
training and education in research. Individuals will train in the research
program of a Mayo Clinic principal investigator. Qualified individuals will
demonstrate the potential for research as evidenced by their training and
peer-reviewed publications and should become competitive for national research
grants. Upon background check and CCATS Executive Committee approval, Research
Fellow may have patient/research subject contact directly relating to and
incidental to the original research program. Proof of English proficiency is
required for J-1 Short-Term Scholars, Research Scholars, Professors,
Specialists, and Student Interns sponsored by Mayo Clinic.

Requirements

• knowledge of either clinical-based research or laboratory-based research often obtained from a postdoctoral program
• demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants

Responsibilities

• molecular cloning
• vector production and characterization
• evaluation of transgene expression and pathway modulation
• integration of functional assays relevant to kidney epithelial biology
• design and conduct experimental studies involving vector engineering, nucleic acid delivery, and mechanistic evaluation of gene and RNA-based therapies in cellular and preclinical models

Benefits

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: No Education Listed
• Number of Employees: 5,001-10,000 employees