Research Associate II, Cell Production & Process Development (iPSC)

United Therapeutics • Medford, MA

1d • Onsite

About The Position

There has never been a more exciting time to join IVIVA, a United Therapeutics company. This position offers someone the opportunity of a lifetime – to see a product into something real, an opportunity to create a human kidney equivalent and save lives on a scale before unknown. The Research Associate II – Cell production and Process Development will perform and contribute to the design of cell studies as well as execute analytical methods to support the production and process development of iPS-derived cells and cellularized 3D scaffolds for the development of autologous 3D printed tissue engineered organs. Perform and assist ongoing optimization of the processes to expand and differentiate iPS cells into various cell types under limited oversight Collaborate with scientists to perform and optimize cellular processes to support the production of iPS-derived renal cells Assist in cell studies to address technical and scientific challenges to expansion and differentiation of iPSC-derived cells Prepare, record and manage materials, reagents, and solutions to support cell production and tissue engineering experiments Write and update standard operating procedures and batch records for various differentiation, isolation, expansion and QC processes Record all laboratory data in the in-house data management system(s) Write and update standard operating procedures for operation and maintenance of laboratory equipment Conduct the technical transfer of assays into the production team or to internal manufacturing, as needed Maintain smooth operations of the lab, including maintenance of lab supplies, monitoring of equipment, providing general lab support and helping identify areas for improvement Follow proper procedures regarding laboratory safety, use of personal protective equipment, and handling of biohazard materials, including human or animal cells and tissues Meet 1:1 with managers to review results and progress

Requirements

• 2+ years of experience in a cell biology, developmental biology or biomedical engineering environment with a Bachelor’s degree in cellular biology, developmental biology, biomedical engineering or related field
• Aseptic Technique and mammalian cell culture
• Knowledge of cell biology
• Ability to initiate and manage day-to-day tasks effectively, including multi-tasking, flexibility and adaptability
• Ability to independently follow experimental methods and protocols
• Technical expertise in iPS culture methods
• Comfortable working in a hands-on laboratory environment and have good attention to detail and good lab practice

Nice To Haves

• 0+ years of experience in a cell biology, developmental biology or biomedical engineering environment with a Master’s degree in cellular biology, developmental biology, biomedical engineering or related field
• Knowledge of flow cytometry
• Technical experience in cell bioreactor culture
• Technical expertise in iPS-differentiation methods

Responsibilities

• Perform and contribute to the design of cell studies as well as execute analytical methods to support the production and process development of iPS-derived cells and cellularized 3D scaffolds for the development of autologous 3D printed tissue engineered organs.
• Perform and assist ongoing optimization of the processes to expand and differentiate iPS cells into various cell types under limited oversight
• Collaborate with scientists to perform and optimize cellular processes to support the production of iPS-derived renal cells
• Assist in cell studies to address technical and scientific challenges to expansion and differentiation of iPSC-derived cells
• Prepare, record and manage materials, reagents, and solutions to support cell production and tissue engineering experiments
• Write and update standard operating procedures and batch records for various differentiation, isolation, expansion and QC processes
• Record all laboratory data in the in-house data management system(s)
• Write and update standard operating procedures for operation and maintenance of laboratory equipment
• Conduct the technical transfer of assays into the production team or to internal manufacturing, as needed
• Maintain smooth operations of the lab, including maintenance of lab supplies, monitoring of equipment, providing general lab support and helping identify areas for improvement
• Follow proper procedures regarding laboratory safety, use of personal protective equipment, and handling of biohazard materials, including human or animal cells and tissues
• Meet 1:1 with managers to review results and progress

Benefits

• Eligible employees may participate in the Company’s comprehensive benefits suite of programs, including medical / dental / vision / prescription coverage, employee wellness resources, savings plans (401k and ESPP), paid time off & paid parental leave benefits, disability benefits, and more.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level