Research Associate I/II, Oligonucleotide Synthesis & Chemistry

Wave Life Sciences • Lexington, MA

9d • $72,000 - $92,000

About The Position

Wave Life Sciences seeks a motivated Research Associate I/II, Oligo Synthesis and Chemistry, to join our team in Lexington, MA. This is an ideal position for an individual with a background in analytical chemistry who thrives in a team-oriented, fast-paced, biotech environment. This candidate will be responsible for fulfilling compound requests to support Discovery-related activities and ensuring sample quality.

Requirements

• Masters Degree with 0-2 years of industry experience or Bachelor’s Degree with 2-4 years of industry experience
• Analytical chemistry background preferred
• Meticulous attention to detail and data integrity
• Excellent organizational and time management skills with ability to multitask
• Excellent communication and problem-solving skills
• Expertise with common laboratory operations, including accurate pipetting, dilution, and UV measurement
• Previous experience with UHPLC and LC-MS operation and analysis strongly preferred
• Previous compound formulation experience strongly preferred
• Understanding of oligonucleotide synthesis, formulation, and characterization preferred

Responsibilities

• Enable timely fulfillment of compound requests while ensuring their accuracy and quality for in vitro/vivo assays
• Analysis of oligonucleotides by LC-MS and UHPLC for identification and purity assessment
• Operation of Hamilton Star liquid handler for high throughput sample preparation in 96-well assay plates
• Perform QC assays such as UV, pH, osmolality, and bacterial endotoxin
• Maintain an accurate and traceable oligonucleotide inventory
• Mentor co-ops on laboratory instrumentation and workflows
• Support general laboratory instrument maintenance and troubleshooting
• Communicate effectively with team members and requestors to enable screening efforts for multiple projects
• Document experimental results in ELN and register relevant sample data
• Interact with Data Science/IT to continually advance the data management systems as needed

Benefits

• This position is eligible for a discretionary annual bonus and discretionary stock-based long-term incentives.
• company-sponsored medical, dental, vision, life, long and short-term disability insurances
• generous paid time off (including a week-long company shutdown in the Summer and the Winter)
• 401K participation with matching contributions
• Employee Stock Purchase Program

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level