Research Associate I-II, Conjugation Chemistry

ADARx Pharmaceuticals Inc.San Diego, CA
4dOnsite

About The Position

We are seeking a highly motivated and qualified individual to join our Discovery Chemistry Department as a Research Associate and work as part of a team to drive success. The successful candidate will support ongoing RNA-based drug discovery projects in several therapeutic areas. This role will be expected to be an active participant and participate in experimental design and planning.

Requirements

  • BS or MS in Chemistry or a related discipline with excellent understanding of organic and analytical chemistry.
  • Previous experience working in an organic synthesis, chemistry or analytical laboratory is preferred.
  • Good working knowledge with a wide range of analytical techniques, especially RP-HPLC and LC-MS.
  • Excellent analytical, communication, and organizational skills.
  • Proficiency working with Microsoft Office Suite Products.
  • Must be able to work independently with supervision as needed.
  • Proficient at working independently as well as in cross-functional team settings
  • Adaptable / Flexible - willing and able to adjust to multiple demands and shifting priorities as well as an ability to meet day-to-day challenges with confidence and professionalism.
  • Self-motivated with excellent interpersonal, organizational and communication skills with the ability to take a hands-on approach to work effectively in a dynamic and collaborative, fast-paced environment.
  • Strong problem-solving skills and a proactive attitude towards exploring new approaches.
  • United States (Required)
  • Background Check
  • As a condition of employment, you must successfully complete all post-offer, pre-employment requirements, including but not limited to a background check.

Nice To Haves

  • Prior experience in biotech/pharmaceutical industry a plus.
  • Previous experience with RNA/oligonucleotide therapeutics is preferred but not essential.

Responsibilities

  • Develop and promote a workplace culture that values diversity of thought, promotes integrity and creates an atmosphere that supports coaching and fosters accountability.
  • Carry out assigned laboratory functions applying knowledge and skill in an accurate, timely manner.
  • Establish and maintain excellent working relationships with critical collaborative partners throughout the company.
  • Synthesis, characterization, and purification of novel oligonucleotide conjugates
  • Identify critical issues/steps in conjugation and solve problems in a timely fashion.
  • Development and optimization of conjugation protocols using novel chemistries and techniques.
  • Track progress against project timelines, generate regular status updates, and communicate progress and issues to management.
  • Manage and maintain equipment, reagents and dedicated laboratory environment needed to carry out assignments; Troubleshoot and solve equipment/technical problems.
  • Maintain updated and well-organized lab notebooks.
  • Execute daily laboratory operations with an approach designed to minimize risks and hazard waste streams.
  • Maintain all appropriate corporate standards for facility safety and hazardous material management.
  • Other duties as assigned.

Benefits

  • Equity-based compensation
  • Performance-based bonuses
  • 401(k) with Company Match
  • Medical, Dental, Vision
  • Flexible Spending Account
  • Life Insurance
  • Employee Assistance Program
  • Employee Discounts
  • Gym Membership
  • Paid Vacation
  • Paid Holidays
  • Paid Sick, Jury Duty, Bereavement
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