Research Assistant III

Jackson Laboratory•Farmington, CT

27d

About The Position

The Hinson lab is seeking a highly motivated and detail-oriented Research Assistant to support a cutting-edge project focused on phenotyping cardiomyocytes derived from genetically diverse human induced pluripotent stem cell (hiPSC) lines. This research is pivotal in understanding the genetic basis of cardiotoxic responses and developing predictive models of cardiovascular health using high-throughput functional screening, transcriptomics, and metabolomics. Additional skills that would be of particular interest to the position include human pluripotent stem cell handling, directed cardiomyocyte differentiation, high-throughput functional assays, contractility analyses and molecular profiling assays such as transcriptomics and metabolomics. The exceptional candidate will work at the intersection of genetics, physiology, and systems biology in a collaborative, multidisciplinary research environment. Gain experience with cutting-edge screening technologies and automated platforms. Contribute to impactful translational research in cardiac safety pharmacology and personalized medicine.

Requirements

Bachelor's degree in Cell Biology, Molecular Biology, Biomedical Engineering, or a related discipline.
Experience with mammalian cell culture, preferably with stem cells or cardiomyocytes.
Familiarity with flow cytometry, fluorescence microscopy, and basic molecular biology techniques.
Strong organizational skills and attention to detail.
Ability to follow and adapt protocols accurately.
Excellent documentation and data management practices.
Team-oriented with strong communication and collaboration skills.

Nice To Haves

Experience in iPSC culture and differentiation, especially in cardiovascular lineages.
Exposure to high-throughput screening platforms (IonOptix, Axion MEA).
Comfort with large-scale cell processing and cryopreservation techniques.
Knowledge of automation tools and liquid handling robotics is a plus.

Responsibilities

Proposes alternative research methods, techniques and initiatives demonstrating knowledge of other scientific areas and related research
Demonstrates scientific knowledge and analytical skills to monitor, modify, and design the research process. Designs, modifies, and troubleshoots highly specialized equipment.
Independently expands scope of literature search to support and/or propose alternative experimental methods, procedures and/or techniques.
Gathers information to prepare budget and proposes estimates for acquisition of supplies and equipment
Analyzes and resolves variations in complex tests, experiments and procedures; designs and implements modifications and changes to techniques, procedures and quality control measures
Leads multiple, concurrent projects and/or multi-faceted projects; directs others in making modifications
Evaluates documentation of results; leads efforts to modify and adapt research methodologies in collaboration with others; ensures compliance with regulatory standards.
Manages laboratory resources, may include budget and personnel; establishes priorities in the use of resources including space, field, equipment and/or facilities.
Understands research goals thoroughly; can instruct and inform others about past and future research directives. Also coordinates with outside collaborators to open new avenues or points of interest of research. Shows a willingness to teach as well as be taught.
The RA III may have direct supervisory responsibilities and is accountable to ensure the effective training and development program for assigned personnel and to identify and develop staff. The RAIII is responsible to develop training and development programs to strengthen technical and management skills.