Research Assistant II

Beth Israel Lahey Health

9d•$22 - $31

About The Position

When you join the growing BILH team, you're not just taking a job, you’re making a difference in people's lives. The McDermott/Mahoney Lab at the Beth Israel Deaconess Medical Center is looking for a highly motivated and dedicated full-time technician to support research on immune evasion mechanisms to resistance to VEGFR tyrosine kinase inhibitor therapy. One focus of the laboratory is on characterization of costimulatory molecules related to PD-1 and PD-L1, such as B7-H7/HHLA2, that are expressed by kidney cancer, and how they regulate the immune response given their potential for cancer therapy by analyzing human tumors and using mouse models. A second focus of the laboratory is characterizing the mechanism of resistance and toxicity from VEGFR tyrosine kinase inhibitor and developing preclinical models to expedite translation of new therapies for patients. The successful candidate will be enthusiastic, self-motivated, dedicated, possess excellent organizational skills, be attentive to detail, and capable of forming effective working relationships with members of the research team with an interest in immunology, optimally experience in cellular immunology techniques and multicolor flow cytometry, and preclinical mouse cancer models.

Requirements

Bachelor's degree in Life Sciences or related scientific field required.
1-3 years related work experience required, including 1 year of related experience or a Master's degree with requisite knowledge and skills.
Experience with computer systems required, including web-based applications and some Microsoft Office applications which may include Outlook, Word, Excel, PowerPoint or Access.

Responsibilities

Performs routine and non-routine laboratory tests which may include DNA sequencing, gene cloning, in situ hybridization, immunohistochemistry, northern blotting; synthesizes and interprets results. (essential)
May operate and maintain moderate to complex lab equipment such as spectrophotometer, flow cytometer, etc. (essential)
Using analytical abilities and sound judgment, makes decisions regarding the reliability and accuracy of results, repeating procedures when necessary. (essential)
May assist with planning specific research procedures and coordinating schedules of tests and procedures (essential)
May prepare written and/or verbal reports on status of research and the technical procedures used, including statistical and graphic summaries of findings and possible conclusions. (essential)
May have technical expertise in specific area(s) that surpasses basic performance expectations (i.e. knowledge/use of the electron microscope), contributes to the laboratory by utilizing this experience (essential)
May demonstrate routine to complex lab techniques to others in the lab. (essential)
Attends Medical Center lectures regarding all safety requirements/conditions.
Attends courses, lectures, and conferences to further own knowledge of research and laboratory techniques, consults with other researchers and technicians to exchange information.
May demonstrate routine to complex lab techniques to others in the lab. (essential)