R&D Scientist

Sino Biological • Houston, TX

80d

About The Position

This position is suited for experienced scientists with a strong background in protein purification, characterization, and bioprocess development in an industrial environment. The Scientist or Senior Scientist will play a key role in leading and executing downstream process development, including chromatography-based purification and recombinant protein quality assessment. The role involves independent design and optimization of purification workflows, supervision of junior staff, and collaboration with upstream and operations teams to support internal pipeline and client-based programs. Responsibilities include method development, hands-on operation of FPLC systems (e.g., Cytiva AKTA), and analytical techniques such as HPLC-SEC, ELISA, and DSF to evaluate product quality and process consistency. The successful candidate will demonstrate strong scientific judgment, attention to detail, and the ability to document and communicate results clearly in a fast-paced, team-oriented setting. Flexibility is required, including potential weekend work and early or late weekday shifts based on project demands.

Requirements

• MS or PhD in Biochemistry, Biotechnology, Molecular Biology, or a related field.
• Several years of relevant experience in recombinant protein and antibody design, expression, purification, and characterization, as well as novel bioprocess development.
• Proficiency in protein characterization assays such as BLI, ELISA, and DSF, and analytical techniques such as HPLC-SEC.
• Strong knowledge of mammalian expression systems and downstream purification workflows, including HEK293/CHO expression and Cytiva AKTA or other FPLC platform applications.
• Industrial experience is preferred.
• Excellent organizational, analytical, and communication skills.
• Willingness to work a flexible schedule, including occasional morning, evening, and weekend hours.
• Must be able to lift and move 25-50 lbs as needed.

Responsibilities

• Lead bioprocessing projects and supervise associates in wet lab activities related to recombinant protein and antibody production.
• Design and improve upstream and downstream bioprocessing workflows, contribute to project planning, and review project information to provide feedback on recombinant protein and antibody design for upstream and downstream processes.
• Develop and optimize assays to evaluate protein interactions, stability, and quality controls, including BLI, ELISA, HPLC-SEC, DSF, and related analytical methods.
• Oversee maintenance, calibration, and troubleshooting of bioprocessing instruments.
• Collaborate with cross-functional teams to ensure alignment with project goals.
• Maintain accurate and organized documentation, including experimental records and technical reports.
• Ensure compliance with laboratory safety practices and OSHA guidelines.

Benefits

• Competitive compensation package.
• Learn directly from industry professionals in a global biotech company.
• Career growth opportunities and mentorship.
• A welcoming, team-first workplace that celebrates diversity and collaboration.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Industry: Chemical Manufacturing
• Education Level: Master's degree
• Number of Employees: 251-500 employees