Purification Post-Doctoral Scientist - Network TSMS

Eli Lilly and CompanyUs, IN
13dOnsite

About The Position

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. Company Overview: Lilly, a leading innovation-driven corporation is developing a growing portfolio of pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Ind., Lilly provides answers – through medicines and information – for some of the world’s most urgent medical needs. Founded over 137 years ago, the company has sustained a culture that values excellence, integrity and respect for people. This has resulted in Lilly frequently being ranked as one of the best companies in the world at which to work. Lilly knows its business has prospered because of its employees – people with a talent for innovation and a passion for making a difference by finding treatments for the most stubborn diseases; people whose talent is matched by their generosity, and people with strong values and a determination to prevail, regardless of the challenges. Join our team – and make a difference in improving health for people all over the world. Responsibilities: Post-Doctoral Scientists at Lilly are responsible for: Ensuring reliability of our manufacturing systems Searching for and implementing innovative improvements Driving technical projects Maintaining our processes in a state of compliance with US and global regulations Designing and developing drug manufacturing and delivery systems The position is a Post-Doctoral scientist position in the Technical Services/Manufacturing Sciences (TS/MS) organization. The TS/MS organization leverages scientific expertise from various fields to understand and ensure product and plant operation (e.g. organic chemists to chemical engineers and biologists). The position will be made available beginning Aug 1, 2025 and will provide technical and scientific support within a dynamic manufacturing environment for the synthesis, purification, and formulation of various small molecules, peptides, and protein products. The successful candidate will be responsible for designing and executing experiments to advance manufacturing knowledge, process optimization and production technical transfer, as needed. Scientists actively contribute to the TS/MS organization, and have extensive opportunities for involvement in cross-functional teams. This position allows for development of a comprehensive understanding of the pharmaceutical industry, Good Manufacturing Practices (GMP), Regulatory Requirements, and the essential role scientists play in creating solutions for Eli Lilly and Company and its patients. Key Objectives/Deliverables: Understanding the scientific principles required for manufacturing intermediates and bulk drug substances, including the interaction of chemistry and equipment. Understand the chemistry and stability of synthetic and biomolecules and associated analytical tools. Develop appropriate laboratory-scale models and methods for key process steps in reactions and purification peptides and biomolecules. Design, conduct, and analyze experiments to deepen process understanding and optimize process steps and reactions. Understand scale-up requirements and, as needed, partner with the various manufacturing plants to conduct appropriate scale-up and investigative work. Provide technical support for other process development areas if needed. Document all work in an appropriate manner. Mentor lab associates to enhance their technical capabilities. Participate in technology transfer to other laboratories/plants as needed.

Requirements

  • Ph.D. in scientific disciplines of Biochemistry, Biology, Chemistry, Chemical Engineering.
  • Understanding of synthetic molecule/peptide chemistry and purification.
  • Demonstrated record of scientific achievement.
  • Demonstrated problem solving abilities.
  • Ability to work well independently, as well as in teams.

Responsibilities

  • Ensuring reliability of our manufacturing systems
  • Searching for and implementing innovative improvements
  • Driving technical projects
  • Maintaining our processes in a state of compliance with US and global regulations
  • Designing and developing drug manufacturing and delivery systems
  • Designing and executing experiments to advance manufacturing knowledge, process optimization and production technical transfer, as needed.
  • Understanding the scientific principles required for manufacturing intermediates and bulk drug substances, including the interaction of chemistry and equipment.
  • Understand the chemistry and stability of synthetic and biomolecules and associated analytical tools.
  • Develop appropriate laboratory-scale models and methods for key process steps in reactions and purification peptides and biomolecules.
  • Design, conduct, and analyze experiments to deepen process understanding and optimize process steps and reactions.
  • Understand scale-up requirements and, as needed, partner with the various manufacturing plants to conduct appropriate scale-up and investigative work.
  • Provide technical support for other process development areas if needed.
  • Document all work in an appropriate manner.
  • Mentor lab associates to enhance their technical capabilities.
  • Participate in technology transfer to other laboratories/plants as needed.

Benefits

  • Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance).
  • In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).

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What This Job Offers

Job Type

Full-time

Career Level

Entry Level

Education Level

Ph.D. or professional degree

Number of Employees

5,001-10,000 employees

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