Production Chemist - Torrance
About The Position
PolyPeptide is seeking Production Chemists at multiple levels (I, II, and III) to support the manufacture of high-quality Active Pharmaceutical Ingredients (APIs) in a cGMP-regulated environment. These roles are critical to our mission of delivering safe, effective, and on-time pharmaceutical products to patients worldwide. Whether you are early in your career or an experienced chemist ready to lead, we offer a clear growth path, hands-on manufacturing experience, and the opportunity to work with advanced peptide synthesis and purification technologies. As a Production Chemist, you will be responsible for executing and supporting peptide manufacturing operations across upstream synthesis and downstream purification, while maintaining strict compliance with cGMP, safety, and quality standards.
Requirements
- Bachelor’s degree in a scientific discipline or equivalent
- High School Diploma with significant GMP manufacturing experience may be considered (Chemist I)
- Chemist I: 0–2 years of relevant experience (peptide manufacturing preferred)
- Chemist II: 3+ years of relevant experience in a regulated environment
- Chemist III: 5+ years of relevant experience with demonstrated leadership and technical expertise
- Peptide synthesis and purification (HPLC)
- cGMP documentation and compliance
- Safe handling of hazardous chemicals and reagents
- Strong communication, teamwork, and time management
- Problem-solving and continuous improvement mindset
Responsibilities
- Execute batch production records (BPRs) accurately and in compliance with SOPs and GxP requirements
- Operate and monitor chemical processes including reactors, drying systems, purification HPLCs, and lyophilization
- Perform in-process controls (IPCs) and interpret analytical results (e.g., HPLC, ninhydrin tests)
- Ensure proper material handling, inventory management, and ERP documentation following ALCOA+ principles
- Maintain high standards of safety, cleanliness, PPE usage, and 5S practices
- Communicate effectively with cross-functional teams including QA, QC, Maintenance, Engineering, and Supply Chain
- Entry-level to early-career role with hands-on manufacturing responsibility
- Works under general supervision following established procedures
- Focused on execution, learning cGMP operations, and building technical expertise
- Ideal for candidates new to peptide manufacturing or regulated production environments
- Experienced individual contributor with increasing autonomy
- Troubleshoots process deviations, supports investigations, and assists with CAPAs and quality documentation
- Trains and mentors Chemist I team members
- Participates in process improvements, tech transfers, and scale-up activities
- Senior-level chemist and technical leader
- Acts as a subject matter expert (SME) for processes and equipment
- Makes operational “go/no-go” decisions with Quality and leadership
- Leads troubleshooting, process optimization, and mentoring of Chemist I & II staff
- Supports production planning, forecasting, and continuous improvement initiatives
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
