About the position
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world. SMDD is seeking outstanding process system engineering candidates to work within the process design and development team. The position presents an opportunity to develop and apply computerized model-based solutions to accelerate the development of new medicines. It also presents the opportunity to work side by side with chemists, analytical chemists, formulation scientists and engineers to develop new technical solutions to accelerate our portfolio. The position will be based in Indianapolis where research is conducted in a new, state of the art development facility.
Responsibilities
- Apply process systems engineering fundamentals towards designing and optimizing pharmaceutical manufacturing processes including solids operations, chemical reactions, and separation processes.
- Design appropriate strategies to apply a variety of computational tools to support the development and scale-up of pharmaceutical manufacturing processes.
- Implement and execute the necessary data analysis, models and/or simulations to support the design or scale-up of pharmaceutical manufacturing processes.
- Analyze and interpret data collected from laboratory experiments and/or from manufacturing.
- Actively participate in the design of process conditions for process understanding or for material production in manufacturing.
- Understand and utilize thermodynamics and material characterization techniques as an informing factor to model-based solutions.
- Develop user-friendly computational tools to be deployed across SMDD to support the development of specific manufacturing platforms.
- Train the SMDD general community in the use of platform computational tools.
- Serve as a member of integrated commercial teams responsible for the development and demonstration of new processes.
- Take leadership in the supervision of the compliance with regulations, guidelines, procedures, and practice governing drug research and development.
- Collaborate closely with multifunctional organizations such as Product Delivery, Project Management, Quality, Manufacturing, and Regulatory.
- Develop the external manufacturing network, oversee activities and install key capabilities within contract manufacturing organizations.
- Engage in a highly collaborative work environment across and beyond SMDD and Lilly.
- Direct and mentor less experienced scientists and engineers to deliver the portfolio and innovation projects.
- Promote diverse thought and experience to deliver innovative solutions that address unmet technical needs.
- Publish and present original research externally, author internal technical documents and develop and document control strategies for new product registration applications.
Requirements
- PhD in Chemical Engineering or related discipline.
- Experience across multiple disciplines of process systems engineering (modeling, optimization, control, statistics, numerical methods, programming).
- Knowledge and experience building fundamental, empirical or hybrid models as appropriate.
- Awareness of simulation tools across scales (DEM, CFD, FEM, PBM etc).
- Experience in parameter estimation and handling of data uncertainty.
- Experience with modeling and simulation and data analytics software packages (e.g Python, MATLAB, gPROMS, Aspen +, GAMS, Pyomo, R).
- Strong foundations in numerical methods, optimization, thermodynamics, and transport phenomena.
- Excellent oral communication and documentation skills.
- Demonstrate ability to effectively collaborate with multidisciplinary teams.
- Demonstrate leadership behaviors with ability to accept challenges, seek opportunities to remove barriers, influence without authority, and lead in areas of uncertainty.
- Demonstrate exemplary teamwork/interpersonal skills.
- Demonstrate problem solving, attention to detail and result oriented behaviors in a fast-paced environment.
Benefits
- 401(k)
- Pension
- Vacation benefits
- Medical, dental, vision and prescription drug benefits
- Flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts)
- Life insurance and death benefits
- Certain time off and leave of absence benefits
- Well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities)
