Process Development Scientist

EMD Millipore Corporation-posted 4 months ago
Intern
Burlington, MA
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In this role, you will proactively pursue and conduct process development studies for the production or purification of viral vectors or therapeutic proteins using MilliporeSigma performance reagents, including detergents, enzymes, stabilizers, and flocculants. You will also assist in the development, design, and execution of experiments aimed at optimizing process reagents to enhance processes such as cell lysis, DNA digestion, virus inactivation, and flocculation, contributing to the overall efficiency and effectiveness of our production methods.

  • Apply knowledge of characterizing analytical techniques, such as qPCR, ddPCR, HPLC, light scattering to assess the performance of additives and propose optimal conditions
  • Support the execution of development studies for traditional unit operation such as sterile filtration, depth filtration, tangential flow filtration, viral reduction filtration, chromatography
  • Involvement in selection and sizing, process optimization, and technology transfer activities associated with the purification of new pharmaceuticals with a focus on Phase I-III drug development
  • Provide consultation to customers through email, telecon or video chat and Document customer interfacing activities through appropriate electronic systems.
  • Collaborate with customer process development groups in the eastern region of the United States and work alongside a team of local MilliporeSigma account managers to provide technical expertise and support to local customers
  • Support clinical and commercial scale customers to implement technologies, using sound scientific and engineering principles, and including identification critical quality attributes and maintenance of critical control parameters
  • Propose new technical ideas/areas for the larger group to advance state-of-the-art
  • Communicate and work effectively in cross-functional teams, influence technical approaches and support strategy execution
  • This position will include Travel of up to 30% within North America region
  • Bachelor’s Degree in Chemical Engineering, Biochemistry, or other Engineering or Life Science discipline.
  • 3+ years of experience in pharmaceutical development or technology implementation.
  • Masters Degree in Engineering.
  • Experience with upstream and/or downstream biomanufacturing process requirements, best practices, and industry standards.
  • Experience with analytical methods, assay development and testing.
  • Highly motivated, self-directed, and able to work independently in a field-based position.
  • Experience producing quality written experimental reports and other appropriate documentation.
  • Exceptional hands-on laboratory, analytical, and technology skills.
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