Principal Software QA Engineer

Veracyte • San Diego, CA

9d • Hybrid

About The Position

We are seeking a highly experienced and collaborative Principal Test Engineer to lead the testing process for applications at Veracyte that directly help our company expand and develop new diagnostic solutions to improve patient outcomes and lower healthcare costs.
The Principal Test Engineer is a senior, hands-on quality leader responsible for defining, executing, and continuously improving the software testing strategy within Veracyte's regulated environment. This role ensures that all software products meet applicable quality, safety, and compliance requirements while supporting efficient delivery processes. The Principal Test Engineer acts as a subject-matter expert in verification and validation (V&V), test automation, risk-based testing, and regulatory compliance, providing technical guidance to junior testers and collaborating closely with engineering, product, and quality functions.

Requirements

• 8+ years of experience in LIMS and/or Salesforce testing, with increasing levels of responsibility.
• Bachelor’s or Master’s degree in Life Sciences, Bioinformatics, Computer Science, or a related field.
• In-depth understanding of laboratory science workflows, particularly in genomics, molecular biology, or clinical research environments.
• Proven experience translating technical requirements into testing strategies.
• Strong communication and interpersonal skills, with the ability to lead cross-functional discussions.
• Demonstrated ability to manage complex projects involving multiple stakeholders, with clear timelines and outcomes.
• Demonstrated strong analytical skills coupled with the ability to find and solve the root cause of problems.
• Solid understanding of GAMP5 risk based computerized systems validation methodology
• Solid understanding of regulatory requirements, including GxP, CLIA, and data integrity frameworks.
• Excellent critical thinking and troubleshooting skills.

Nice To Haves

• Familiarity with Agile software development methodologies.
• Familiarity with testing tools such as Jira and requirements tools such as Jama.

Responsibilities

• Act as key point of contact for testing and QA aspects of releases, providing testing services and coordinating with internal resources.
• Develop and execute test strategies (functional, regression, integration), & test cases, Develop supporting test plans and reports
• Serve as a liaison between internal technical teams, and third-party software vendors where applicable
• Manage and prioritize testing related projects, ensuring timely delivery within scope and with a focus on quality and long-term sustainability.
• Identify opportunities for continuous improvement and potential automation of testing strategies and processes.
• Ensure adherence to regulatory and data integrity standards across computerized systems.
• Mentor/coach junior level test team members.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Number of Employees: 251-500 employees