Principal Scientist - In Vitro Pharmacology
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About The Position
In your role as Principal Scientist - In Vitro Pharmacology you will be responsible for development of cell-based assays for emerging targets and functional screening of drug candidates to guide candidate design and selection. You will work with diverse modalities: peptides and proteins, and small molecules, as well as occasionally oligonucleotides, and their conjugates. You will contribute to early screening strategy and execution to ensure identification of hits and lead candidates with desired in vitro potency, efficacy and selectivity. You will evaluate and implement new bioassay techniques and in vitro pharmacology protocols and recommend acquisition and application of instrumentation and technologies within high throughput screening and mechanistic biology. You will display subject matter knowledge within in vitro biology and pharmacology throughout early-stage drug discovery, with a solid understanding of the role of other scientific disciplines in applied drug research. You will be responsible for developing, executing, and documenting experimental procedures and ensuring that data is interpreted, processed, and stored in line with FAIR data principles.
