Principal Scientist II (PRD)

Cambrex • Niwot, CO

238d • $109,000 - $126,500

About The Position

Cambrex is seeking a highly motivated Sr. Principal Scientist II for the Process Chemistry department. This position performs routine and complex organic synthesis, purification, and analytical evaluation of materials as part of a process chemistry research and development team. The chemist will optimize synthetic routes to active pharmaceutical ingredients for purity, reproducibility, scalability, and yield. Experience in process chemistry research and development is desirable. Designs and proposes new synthetic routes to drug substances. May be asked to lead process chemistry portion of customer projects and potentially a group of process chemists. Presents work internally and externally to clients or regulatory agencies.

Requirements

• PhD in Organic Chemistry with 0-12+ years of experience in related industry, or MS in Organic Chemistry with 3-18+ years of experience in related industry, or BS in Organic Chemistry with 9-24+ years of experience in related industry.
• Advanced to expert understanding of general chemistry and organic chemistry.
• Understanding of modern organic synthesis reactions, isolations, and purification procedures.
• Full understanding of common synthetic organic reaction mechanisms.
• Understanding and proficient use of all relevant analytical techniques and instrumentation such as NMR, IR, MS and HPLC.
• Expertise in laboratory glassware and organic chemistry reaction set up, isolation and purification.
• Must demonstrate proficiency in synthesis and purification techniques on scales ranging from milligrams to kilograms.
• Good written and verbal communication skills.
• Familiarity with computer software such as ChemDraw, Microsoft Word, PowerPoint, and Excel.
• Aptitude and willingness to gain more skills & knowledge.
• Good attention to detail and good problem-solving skills.
• Clear and concise communication skills.
• Effectively presents ideas and concepts.
• Demonstrates leadership skills.

Responsibilities

• Carry out multistep organic syntheses, isolation, and purification of targeted products independently.
• Contribute to the strategic approach used to optimize reactions, isolations, and purifications.
• Proficiently conduct analysis of starting materials, reaction mixtures, intermediates and products using appropriate instrumentation.
• Work closely with other chemistry and analytical laboratory staff to coordinate project activities and resource usage.
• Routinely generate summaries and reports on completed experimental work for internal and external use.
• Routine presentation of experimental work for internal meetings and teleconferences with customers.
• Work to ensure that teamwork and cooperation exists within the group at all times.
• Conduct laboratory operations in a safe manner.
• Maintain familiarity with the company's chemical hygiene plan.
• Exhibit safety awareness and safe work practices.
• Follow responsible actions regarding chemical disposal.
• Maintain compliance with all regulations at the federal, state, and local levels.
• Address routine administrative requirements in a timely fashion.
• Demonstrate effective communication skills (both written and oral).
• Participate in project team meetings with customers.
• Work closely with manufacturing and GMP operations to coordinate project-related equipment and activities.
• Assist in the transfer of processes to the manufacturing team.
• Independently designs and proposes new synthetic processes to produce the drug substance.
• May act as process chemistry lead for customer projects.
• Identify critical questions to be answered and set priorities for the process chemistry team.
• Maintain familiarity with applicable literature including organic chemistry and techniques.
• Participate in setting strategy and timing needed for customer proposal requests.
• Routinely generate summaries and reports on completed experimental work for internal and external use.
• Oral and written presentation of experimental work for internal meetings and teleconferences with customers.
• Perform other related duties as assigned.

Benefits

• Medical insurance
• Dental insurance
• Vision insurance
• Life insurance
• Long-term disability insurance
• Generous vacation in your first year
• Sick time
• Retirement savings

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Industry: Merchant Wholesalers, Nondurable Goods
• Education Level: Ph.D. or professional degree