Principal Scientist, Drug Metabolism and Pharmacokinetics

GenentechSouth San Francisco, CA
180d$143,200 - $265,900

About The Position

The Drug Metabolism and Pharmacokinetics (DMPK) department at Genentech is seeking a highly motivated leader who will be supporting small molecule projects in discovery and development. The DMPK group is dedicated to enabling the discovery, development and commercialization of safe and effective medicines by elucidating the absorption, distribution, metabolism, excretion and pharmacokinetic properties of small molecule drug candidates. We accomplish this through the application of state-of-the-art technologies and sciences of bioanalysis, drug metabolism, drug transport and pharmacokinetics. The DMPK group works in close partnership with disciplines such as medicinal chemistry, pharmacology, toxicology, pharmaceutical sciences, clinical pharmacology and regulatory to optimize leads, select clinical candidates, conduct preclinical development studies, support clinical evaluation and contribute to IND and NDA filings. The individual would lead the DMPK strategy, design and execute non-clinical studies in a highly collaborative project team environment.

Requirements

  • PhD degree in pharmacokinetics, drug metabolism or other relevant fields
  • 2 years of relevant pharmaceutical industry experience as a DMPK project leader
  • Proven scientific expertise in supporting discovery and or development projects
  • Good communication, collaborative and organizational skills
  • Ability to work in multifunctional teams

Nice To Haves

  • Experience as a member/leader of multi-functional project teams supporting diverse modalities (small/large molecules, peptides, etc.)
  • Modeling skills

Responsibilities

  • Representation of DMPK at multi-functional discovery and development project teams
  • Lead DMPK strategy as it relates to regulatory setting/interactions
  • Author reports/sections for regulatory briefing packages/filings

Benefits

  • Relocation benefits available
  • Discretionary annual bonus based on individual and Company performance

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Industry

Chemical Manufacturing

Education Level

Ph.D. or professional degree

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