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At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. We are searching for the best talent for a Principal Scientist, Discovery Bioanalysis to be located in Spring House, PA. The Principal Scientist will join the Discovery Bioanalysis group within the Bioanalytical Discovery and Development Sciences (BDDS) organization. The Discovery Bioanalysis group develops fit for purpose methods to provide PK, TK, target engagement, and biomarker quantitative data to meet the fast-paced requirements of therapeutic discovery teams across all therapeutic areas and modalities. They will develop bioanalytical methods using various technical platforms (e.g. hybrid LC/MS-MS, immunoassay, qPCR, etc.) based on project strategy to enable internal decisions to critical questions related to PK/PD, TK, mechanism of action, biodistribution, biotransformation, and matrix stability of therapeutic candidates. They will be focused on establishing platform capabilities for bioanalytical assessments of therapeutic proteins and novel modalities (e.g. antibody-drug conjugates, oligonucleotides, etc.) to support selection and early preclinical safety assessment of lead candidates.