Legend Biotech is seeking a Principal Scientist, CMC Pipeline Innovation as part of the Technical Development team based in Somerset, NJ. The Principal Scientist, CMC Pipeline Innovation is a lab-based role focused on advancing analytical innovation to support the development and manufacturing of pipeline therapies. This position emphasizes the evaluation, development, creation, and integration of advanced analytical technologies to improve method robustness, data quality, and operational efficiency across the product lifecycle. The role involves contributing to internal innovation initiatives and participating in collaborations with external partners to enhance analytical workflows that support scalability, regulatory compliance, and cost-effectiveness. The individual may also support business case development for new technologies that improve patient access through better product understanding and control. This position works closely with cross-functional teams to implement novel analytical approaches across the entire development pipeline, ensuring alignment with evolving regulatory expectations and emerging scientific advancements. A key aspect of the role includes designing and executing proof-of-concept studies across multiple modalities and development stages, demonstrating the feasibility, scalability, and impact of innovative analytical solutions. These studies inform strategic decisions, guide technology adoption, and ensure that innovation efforts are broadly applicable and sustainable across the full portfolio of pipeline programs.