Principal Scientist, Biologics Discovery
About The Position
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com. As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit. About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine We are searching for the best talent for a Principal Scientist, Biologics Discovery in Spring House, PA. Job Description Position Summary: This position is dedicated to advancing the discovery and development of innovative biotherapeutics targeting unmet medical needs through immune-mediated approaches. As a key contributor, you will leverage your expertise in Immunobiology and T-cell biology to support portfolio programs and drive the success of discovery initiatives.
Requirements
- Ph.D. degree in life sciences (molecular biology, biochemistry, immunology, or a related discipline) with 4+ years post-doctoral experience OR Master’s Degree in life sciences with at least 6+ years of experience is required.
- Extensive understanding of immunology, including in vitro and in vivo models relevant to immuno-oncology and autoimmune disease.
- Demonstrated experience with immune cell based assays such as multi-color flow cytometry, cytotoxicity, and multiplex cytokine assays.
- Experience developing novel, complex, and high-throughput immune assays for functional characterization and MOA studies.
- Ability to work effectively in a matrixed environment—both within the group and across the broader organization.
- Strong dedication, motivation, and a collaborative approach to advancing therapeutic innovation.
- Commitment to continuous learning and scientific excellence.
- Excellent analytical and problem-solving skills for experimental design and data interpretation.
- Exceptional communication skills, with the ability to present complex data clearly and concisely is required.
Nice To Haves
- Experience in end-to-end drug development processes is highly preferred.
- Industry experience is highly preferred.
Responsibilities
- Leading or actively participating in project teams to progress discovery portfolio projects.
- Driving technology development efforts for multispecific antibody platforms and validating readiness for portfolio inclusion.
- Designing, conducting, and interpreting in vitro immune cell functional assays and related experimental studies.
- Presenting and defending scientific findings independently within multidisciplinary teams and initiatives.
- Authoring patent applications, manuscripts, study protocols, SOPs, and technical reports.
- Managing and mentoring scientific staff.
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Ph.D. or professional degree
