Principal Research Associate, Flow Cytometry

Sana Biotechnology • South San Francisco, CA

2d • $115,000 - $145,000 • Onsite

About The Position

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As a Principal Research Associate, Flow Cytometry, you will report to the Scientist, Flow Cytometry. You will either lead or support the development and implementation of flow cytometry methods for Sana’s cell therapy products, and support method transfer and qualification to enable GMP testing. This role is onsite in South San Francisco, CA.

Requirements

• Bachelor’s plus 6 years or MS with 4+ years or equivalent combination of education and work experience
• Experience with developing and qualifying multi-color flow cytometry assays for pluripotent stem cell or stem cell-derived pancreatic islet cell products per FDA, ICH, and USP regulatory guidelines
• Proficient in independently analyzing flow cytometry data using FlowJo and/or FCS Express, drawing conclusions, and making recommendations for next steps
• Experience with performing mammalian cell culture and generating cell stocks using aseptic techniques
• Ability to multitask, communicate effectively, and quickly adapt to changing business conditions
• High degree of self-motivation and accountability

Nice To Haves

• Experience using statistical software such as JMP for DOE, data visualization, and analysis
• Experience with development of analytical methods for commercial cell-based therapeutics
• Experience working in a Quality Control function to support GMP testing

Responsibilities

• Develop and qualify multi-color flow cytometry assays to support the characterization, process development, release testing, and stability testing of cell therapy products
• Culture, bank, and characterize mammalian primary cells and immortalized cell lines for use in assay development or as controls
• Create detailed documentation of experimental procedures and results in the electronic laboratory notebook and complete the review and approval of notebook entries per established policy
• Give scientific presentations, prepare technical reports, and draft/revise analytical test methods
• Perform calibration, maintenance, and troubleshooting of instruments and reagents
• Maintain inventory of reagents and improve operational efficiency in the laboratory, adhering to laboratory safety standards
• Contribute to flow cytometry best practices and keep pace with innovations
• Support Quality Control on method transfer, qualification, and testing at CDMOs as well as internal laboratory operations and testing as needed

Benefits

• For benefit eligible employees, we cover a generous portion of the cost for employee health coverage, making high-quality care more accessible and affordable.
• We offer ample time-off (various paid time off benefits, such as holidays, vacation, sick time, and parental leave), short- and long-term disability, employer paid basic life insurance, additional voluntary life insurance protection, financial wellness programs including financial planning resources, a 401(k) Plan with an immediately vested employer match, Tuition Reimbursement and Student Loan Repayment, Employee Stock Purchase Plan, commuter subsidy and a variety of wellness offerings to support each person individually.
• For more details on our benefits, visit Sana’s Benefits Portal.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal