Principal IT Delivery Program Manager | Onsite San Diego HQ

Neurocrine Biosciences•San Diego, CA

2d•Onsite

About The Position

The Principal IT Delivery Program Manager is a senior execution leader responsible for driving the successful delivery and value realization of complex, enterprise-scale technology initiatives. Operating within the Value Management Office (VMO), this role ensures disciplined program execution across infrastructure, cloud, cybersecurity, and enterprise platforms. This individual brings deep infrastructure domain expertise and structured program management rigor to lead cross-functional initiatives that are critical to business performance, regulatory compliance, and operational scalability. The role is highly execution-focused, emphasizing governance, risk management, stakeholder alignment, and measurable outcomes.

Requirements

Bachelor’s degree in Computer Science, Information Technology, or related field with 6+ years of IT experience in a pharmaceutical/biotech environment with FDA regulatory exposure, OR Master’s degree in a related field with 4+ years of relevant experience
Strong experience managing enterprise infrastructure programs across cloud, network, and data center environments
Proven experience leading system/platform migrations and multi-cloud hybrid implementations
Experience supporting validated applications in regulated environments
Strong program and project management expertise (PMP certification preferred or in progress)
Experience with ITSM integration and service delivery (e.g., ServiceNow)
Demonstrated ability to manage risk, drive structured escalation, and lead complex cross-functional programs
Strong financial acumen with experience managing budgets and forecasting

Nice To Haves

PMP and/or ScrumMaster certification
Trained in Agile Frameworks
Experience working with enterprise infrastructure vendors and managed service providers
Change advisory board experience
Advanced knowledge of infrastructure technologies including cloud platforms, networking, and platform engineering
Experience operating in highly matrixed, global organizations

Responsibilities

Lead large-scale, multi-domain initiatives including cloud migrations, network modernization, data center upgrades, and managed service transitions
Drive structured program execution including milestones, dependencies, RAID logs, and executive reporting
Ensure delivery is on time, within scope, and aligned to enterprise roadmaps and business goals
Translate technical complexity into clear business impact and decision-ready insights
Design and implement scalable L1/L2 managed service models
Lead vendor onboarding, transition planning, and operational readiness
Establish SLA/KPI governance and service performance management frameworks
Drive integration between infrastructure monitoring platforms and ITSM systems (e.g., ServiceNow)
Implement runbooks, escalation models, and operational accountability structures
Establish and maintain program governance cadence including executive-level reporting
Identify and mitigate cross-domain risks across infrastructure, cybersecurity, and compliance
Ensure validation, regulatory, and security requirements are embedded into delivery plans
Maintain documentation and traceability to support audit readiness in regulated environments
Manage strategic vendor relationships across cloud, network, and infrastructure providers
Drive vendor accountability through structured governance forums
Track budgets, forecast financial impact, and support cost optimization initiatives
Ensure resource and capacity planning aligns with program delivery needs
Partner with IT and business leaders to align infrastructure solutions with enterprise needs
Translate business requirements into scalable, compliant technology solutions
Drive alignment across Cybersecurity, Architecture, Engineering, and Operations teams
Communicate effectively with executive stakeholders to influence decisions and remove barriers

Benefits

retirement savings plan (with company match)
paid vacation, holiday and personal days
paid caregiver/parental and medical leave
health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans
annual bonus with a target of 30% of the earned base salary
eligibility to participate in our equity based long term incentive program

Stand Out From the Crowd

Upload your resume and get instant feedback on how well it matches this job.

Upload and Match Resume