Principal Engineer

Mayo Clinic • Rochester, MN

9h

About The Position

This position supports Engineering’s mission to drive innovation and new product
development at Mayo Clinic, with a unique opportunity to help define the next
generation of tools and technologies that enable us to deliver better care for
our patients. The role contributes to Mayo Clinic’s commitment to transforming
healthcare and improving patient outcomes through innovation and excellence by
developing cutting-edge solutions and leveraging emerging technologies.

We are seeking an experienced Principal Software Engineer with expertise in Edge
AI/ML development, wireless communication, engineering test tools
(hardware/software), and embedded systems. The position will have the following
responsibilities:

Leads and/or is a part of Engineering Teams that Design and develop components
of biomedical-related engineering systems, applying knowledge of complex
principles, theories, concepts, tools and techniques to the design challenges. May act as Technical Lead for projects to provide technical and work direction
to project team members and while completing technical work as needed. May act
as a liaison to other Mayo development groups (Facilities, IT, Digital Health,
etc.) in performing Technical Lead activities. May mentor and coach other staff
as required. Developing skills in one or more engineering disciplines.
Developing expertise in the use of software modeling and analysis tools and
techniques. May lead in evaluating new technologies and capital equipment. Has
software-specific expertise in safety risk management. Working to develop
expertise in regulatory requirements applicable to his/her unit. Self-starter
who functions effectively in a multi-disciplinary development environment.
Demonstrated ability to effectively communicate with team members, physicians
and health care providers. Possesses effective oral communication and
presentation skills. Develops engineering and technical documentation.

Requirements

• Expertise in Edge AI/ML development
• Expertise in wireless communication
• Expertise in engineering test tools (hardware/software)
• Expertise in embedded systems
• Knowledge of complex principles, theories, concepts, tools and techniques to the design challenges.
• Demonstrated ability to effectively communicate with team members, physicians and health care providers.
• Possesses effective oral communication and presentation skills.
• Develops engineering and technical documentation.

Responsibilities

• Lead teams in the design, development, and optimization of Edge AI systems for real-time performance and scalability.
• Lead development teams in the integration of Edge AI Systems into other Clinical and Research processes and workflows.
• Identify the institutional tools, components, and systems necessary to fully integrate Edge AI Systems into Mayo practice.
• Analyze and Integrate AI models into embedded systems and ensure compatibility with hardware platforms.
• Work with serial communication protocols (e.g., I2C, SPI, UART, CAN) to enable seamless hardware-software interaction.
• Collaborate with cross-functional teams to ensure compliance with regulatory requirements, safety risk management, and industry standards.
• Perform unit, integration, and system-level debugging and optimization to enhance performance and reliability.
• Lead code reviews, mentor junior engineers, and drive best practices in software development.

Benefits

• Medical: Multiple plan options.
• Dental: Delta Dental or reimbursement account for flexible coverage.
• Vision: Affordable plan with national network.
• Pre-Tax Savings: HSA and FSAs for eligible expenses.
• Retirement: Competitive retirement package to secure your future.

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: No Education Listed