The Postdoctoral Research Associate will focus on the pathogenesis of host pulmonary responses to injuries, including infectious agents. A central area of interest will be on host responses to injury that produce airways ectasia, e.g., bronchiectasis and/or bronchiolectasis. Topics of interest in this context would include: 1) the role of obstruction and luminal/epithelial hypoxia in pro-inflammatory/pro-ectatic airway responses; 2) the roles of anaerobic bacteria in the pathogenesis of ectasia; and 3) genes that both initiate and modify ectatic lung diseases. The studies will utilize high-content spatial transcriptomics and proteomics technologies, aerobic/anaerobic cell culture technologies, single-cell RNAseq technologies, Qpath/Visiopharm/site-based image analyses, murine studies, histology, qPCR, and interface with explanted human lungs for translational studies. Essential duties of the Postdoc include: Designing and carrying out studies; Analyzing and interpreting data; Publishing papers describing these results, all with the mentor.
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Education Level
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Number of Employees
11-50 employees