The laboratory of Richard Mailman, Professor of Pharmacology and Neuroscience at the University of Virginia, School of Medicine, is seeking a post-doctoral scholar who is interested in diseases of the brain and development of novel therapeutics. The Mailman lab focuses on mechanisms of drug receptor interaction, and the discovery and development of CNS drugs. Our laboratory discovered the first selective full agonist for the dopamine D1 receptor. We took this project from an idea to clinical trials and showed that it might be the first novel treatment of Parkinson's disease, an idea proven with three Phase 3 clinical trials last year. During this same period of time, we discovered a novel signaling mechanism termed functional selectivity (biased signaling) and demonstrated that this mechanism was critical in the actions of the first third generation antipsychotic drug. We are now poised to continue these advances and would like to recruit a scientist with an interest in brain disorders and their molecular, biochemical, and behavioral manifestations. We have collaborations with other labs that enrich the overall research experience.
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Industry
Executive, Legislative, and Other General Government Support
Education Level
Ph.D. or professional degree
Number of Employees
101-250 employees