Postdoctoral Research Associate - Oncology

Washington University in St. Louis • St. Louis, MO

88d

About The Position

The laboratory of Dr. Kian Lim at WashU Medicine in St. Louis, MO, is currently seeking driven and accomplished individuals for a postdoctoral fellow position. This interdisciplinary role will focus on investigating mechanisms of treatment resistance in gastrointestinal cancers, with a specific emphasis on pancreatic neuroendocrine and biliary tract cancers and exploring the roles of KRAS pathway inhibition and inflammatory pathways mediated by TNF, TGF-β, and the IL-1R/TLR axis. The overarching goal of our research is to develop novel therapeutic regimens that can be advanced into clinical trials for cancer patients. Successful candidates will be responsible for conducting experiments using basic bench techniques, performing assays such as western blots, cell cultures, and molecular cloning, and analyzing genomic and transcriptomic datasets with help from bioinformatician already in the lab. Strong candidates must hold a Ph.D. in a relevant field and must possess proficiency in molecular biology techniques including western blots, cell cultures, molecular cloning, PCR and other typical wet bench techniques. The successful candidate must also have experience and be comfortable with handling experimental and transgenic mouse models. The Lim Lab fosters a culture of respect, honesty, and hard work and is committed to translating preclinical findings into clinical trials for patients with gastrointestinal cancers.

Requirements

• Ph.D., M.D. or equivalent terminal or doctoral degree.
• Proficiency in molecular biology techniques including western blots, cell cultures, molecular cloning, PCR and other typical wet bench techniques.
• Experience and comfort with handling experimental and transgenic mouse models.

Nice To Haves

• Collaboration skills.
• Data analysis and interpretation skills.
• Experience with flow cytometry and immunohistochemistry (IHC).
• Familiarity with informatics and in vitro/in vivo assays.
• Proficiency in laboratory operations and techniques.
• Knowledge of omics and programming languages such as Python and R.
• Scientific writing skills.

Responsibilities

• Manages their own project, which should lead to a first author publication.
• Develops expertise in molecular biology and tumor immunology.
• Develops proficiency in career skills, including writing, public speaking, networking, and critical evaluation of scientific literature.
• Presents scientific work both inside and outside the University with excellent oral communication skills.
• Assists with grant preparation and reporting.
• Prepares and submits papers on research.
• Assists in the design of research experiments.
• Evaluates research findings and assists in the reporting of the results.
• Conscientious discharge of their research responsibilities.
• Maintains conformity with ethical standards in research.
• Maintains compliance with good laboratory practice including the maintenance of adequate research records.
• Engages in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
• Collegial conduct towards co-trainees, staff members and members of the research group.
• Adherence to all applicable University policies, procedures and regulations.

Benefits

• Comprehensive and competitive benefits package.
• Eligibility for benefits is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree