The Pottier Laboratory at WashU Medicine is excited to announce an opening for a Postdoctoral Research Associate. The overarching goal of the laboratory is to identify disease associated events that may serve as both therapeutic targets and biomarkers for early onset dementia such as early onset Alzheimer’s disease and frontotemporal dementia. Our research leverages comprehensive genomic, transcriptomic, and proteomic analyses within highly characterized and unique cohorts. We are looking for a postdoctoral fellow that will lead projects that involve genomics, transcriptomics and proteomics. The successful candidate will leverage unique population cohorts and innovative approaches to discover pathways related to disease presentation. The Pottier Laboratory is part of the NeuroGenomics and Informatics Center at WashU. We are dedicated to generating and analyzing whole-genome sequencing data along with high-throughput, multi-dimensional 'omics' data to advance our understanding of neurodegeneration. WashU Medicine is renowned for its research cohorts of neurodegenerative disorders, which include clinical, neuropathology, neuroimaging, and fluid biomarker phenotypes. Recent publications on the subject: Pottier et al., “Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing”, Nature Communications, 2025. Patel et al., “Whole genome sequencing reveals the impact of lipid pathway and APOE genotype on brain amyloidosis”, Hum Mol Gen, 2025. Bradley et al., “Proficiency in conducting association studies and/or single nuclei RNA sequencing analyses.”, Alzheimer’s and Dementia, 2025. Kouri et al., “Clinicopathologic Heterogeneity and Glial Activation Patterns in Alzheimer Disease”, JAMA Neurol, 2024. Pottier et al., “Shared brain transcriptomic signature in TDP-43 type A FTLD patients with or without GRN mutations”, Brain, 2022. Job Description Primary Duties & Responsibilities: Information on being a postdoc at Washington University in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/ . Trains under the supervision of a faculty mentor including (but not limited to):