Postdoctoral Fellow - Kaushansky Lab We are seeking a postdoctoral fellow to join our interdisciplinary team (Kaushansky Lab, Seattle Children's Research Institute) that investigates host-parasite interactions of the malaria-causing parasite Plasmodium. Soon after the Plasmodium parasite is transmitted to the mammalian host, the parasite resides within the liver. During its liver residence, the parasite infects a hepatocyte, stretching its host cell to 50-100 times its normal volume. However, not all parasites are successful and some are eliminated by hepatocyte cell death (engaging multiple cell death pathways). If this stage of infection was completely blocked, it could stop all disease and transmission, and induce protective immunity against subsequent infection. For this reason, liver infection is of great interest to our laboratory: we see it has a strong interventional target for malaria, but also see malaria-causing parasites as a powerful tool to probe the limits of liver biology and immunology. This postdoctoral fellow will ask fundamental biological questions about host parasite interactions in the liver, particularly with respect to how the cell death pathways that are engaged in the hepatocyte inform subsequent immune responses. Interested applicants should provide a cover letter detailing their scientific achievements, goals, and a description of their interest, in addition to a curriculum vitae that indicates their education, experience, and qualifications.
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Job Type
Full-time
Education Level
Ph.D. or professional degree
Number of Employees
5,001-10,000 employees