Postdoctoral Fellow

Tulane University • New Orleans, LA

50d

About The Position

The Postdoctoral Fellow for the Department of Biochemistry and Molecular Biology will be responsible for studying the biochemical and molecular mechanisms underlying the regulations of the p53-MDM2 loop, mutant p53s, and the c-Myc pathway in response to various signals and to identify small molecules that can suppress tumor growth by re-activating p53 activity or suppressing c-Myc activity in human cancer cells and mouse tumor model systems including genetically manipulated mouse models, such as p53-null, MDM2-C305/MDM4-3SA double knockin, CCDC3-null, TA-p63-null, PHLDB3-null, and p53-R249S knockin mouse models.

Requirements

• Ph.D. or M.D., within 6 months of hiring.
• Research experience in biochemistry, enzymology, protein biochemistry, and molecular and cellular biology, mouse tumor models, and mouse genetics.

Responsibilities

• studying the biochemical and molecular mechanisms underlying the regulations of the p53-MDM2 loop
• studying mutant p53s, and the c-Myc pathway in response to various signals
• identify small molecules that can suppress tumor growth by re-activating p53 activity or suppressing c-Myc activity in human cancer cells and mouse tumor model systems including genetically manipulated mouse models, such as p53-null, MDM2-C305/MDM4-3SA double knockin, CCDC3-null, TA-p63-null, PHLDB3-null, and p53-R249S knockin mouse models

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Industry: Educational Services
• Education Level: Ph.D. or professional degree
• Number of Employees: 1,001-5,000 employees