Postdoctoral Fellow/Trainee
About The Position
The Janiszewska lab dissects the ecosystem of aggressive brain tumors to identify novel vulnerabilities of these incurable tumors. The lab employs a variety of techniques, including confocal microscopy, spatial transcriptomics and in vitro and in vivo models to study brain tumor cell-cell interactions and the organization of the cancer ecosystem. We strive for highly collaborative and inclusive lab environment. Trainees will have ample opportunities to interact with researchers in the department, across our campus and with external collaborators. One of the major challenges contributing to poor survival of patients with brain tumors is the intratumor heterogeneity. Cancer cells with different properties, including different sensitivity to treatment, often co-exist within a tumor, leading to relapse and disease progression. Our goal is to understand the dynamics of intratumor heterogeneity and its functional implications in disease progression in highly aggressive brain tumors. We believe that understanding the interactions between subclonal populations of cancer cells as well as interactions between cancer cells and tumor microenvironment cells holds a key to uncovering more effective treatments for brain tumor patients. This is an exciting opportunity to contribute to research aiming to improve dismal prognosis for brain tumor patients. Duration Minimum of 2 years with advancement to the second-year dependent upon satisfactory progress during the first year. The appointment may be extended over 2 years, contingent on funding and satisfactory performance.
Requirements
- Graduation from an accredited college or university with a PhD/MD in one of these fields of Cancer Biology, Neuroscienceor a related field.
- Minimum of 2 years’ experience in cell culture, in vivo work, confocal microscopy or computational analysis of RNAseq in R/Python.
- Excellent written and verbal communication skills
- Proven ability to work independently and with a team
- Demonstrated proficiency with molecular/cell biology techniques
Nice To Haves
- Experience with primary cell culture, xenograft models, brain tumor biology, confocal imaging, immunofluorescence and/or FISH and/or computational analysis of scRNAseq/RNAseq/spatial transcriptomics
- Background in brain tumor biology
Responsibilities
- The postdoctoral fellow will be responsible for characterizing in vivo and in vitro cell-cell interactions to model heterogenous brain tumors and assess their response to various stimuli.
- This includes designing and conducting experiments, data analysis, manuscript preparation, conference presentations and applying for fellowships/grants.
Benefits
- The University of Colorado offers a comprehensive benefits package.
- The University of Colorado provides generous leave, health plans and retirement contributions that add to your bottom line.
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What This Job Offers
Job Type
Full-time
Career Level
Entry Level
Education Level
Ph.D. or professional degree
