Postdoctoral Fellow - Radiochemistry & Theranostics Approach
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About The Position
We are seeking a radiochemistry postdoctoral fellow to work in Dr. Krebs' lab, in the Department of Nuclear Medicine at MD Anderson Cancer Center. The primary focus of the Krebs Laboratory is the development and preclinical evaluation of imaging and therapeutic (theranostic) agents in conjunction with cellular engineering. The project(s) involve the development and preclinical evaluation of theranostic radiohaptens in conjunction with cellular engineering as well as antibodies for use in immunoPET/SPECT and radioimmunotherapy, radiolabeling of various chelators, haptens and antibodies for example with 89Zr, 68Ga, 225Ac, 86Y, 161Tb, 177Lu including purification techniques and characterization through HPLC and iTLC. Learn in vitro cell culture studies and in vitro assays with radiolabelled haptens and antibodies including cellular uptake, saturation binding, competitive binding, kinetic assays, antibody internalization, and survival assays. In vivo studies include molecular imaging studies including PET and SPECT imaging, pharmacokinetic analyses, ex vivo biodistribution analyses, autoradiography, and immunohistochemistry. Assessment of treatment efficacy and toxicity, e.g., using caliper measurements, bioluminescence imaging, and blood draws. Learn experimental design, data collection, and analysis. Literature review. Write scientific articles. Develop presentation skills in lab meetings and conferences. Supervising, teaching, and mentoring of students/lab personnel. Build a scientific network through interdisciplinary collaborations and attending and presenting at conferences. Develop grant writing skills and leadership skills. Develop independent research project.
