The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the 'holy grail' in medical research, the discovery of strategies for primary prevention. We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD. We are seeking an enthusiastic and self-motivated Postdoctoral Fellow with significant experience in analysis of single nucleus RNA-sequencing (snRNA-seq) data to join our interdisciplinary research team at the Lieber Institute for Brain Development located on the Johns Hopkins medical campus in Baltimore, Maryland. This position is open to computational neuroscientists seeking a position within a translational research setting with a focus on analysis of single cell and spatial transcriptomics data in postmortem human brain tissue. In particular, we are studying gene expression changes associated with major depressive disorder (MDD) and comorbid opioid use disorder (OUD) in the human habenula and other key hubs of reward circuitry with the goal of better understanding addiction and neuropsychiatric disorders. Candidates should have training in neuroscience and previous experience analyzing single cell RNA-seq datasets. Expertise in reward circuits and molecular mechanisms underlying stress and addiction is highly desirable.