Postdoctoral Fellow - Computational Biophysics

Genentech • Daly City, CA

2d

About The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Genentech.
A Postdoctoral fellow position is available for a highly motivated and independent candidate to join the Computational Biophysics Team in the Department of Pharmaceutical Development at Genentech. Our computational biophysics team drives the development of advanced, physics-based in silico methods aimed at understanding the developability properties of therapeutic molecules and providing molecular-level insights. By supporting research and development teams, we enable the implementation of mitigation strategies and facilitate informed decision-making to achieve long-term molecular stability. This postdoctoral position offers an opportunity to contribute to development-focused initiatives. Key areas include generating a molecular-level understanding of self-association and developing guiding tools and methods to support formulation development. Candidates with experience in protein self-association, interfacial behavior, and the effects of salts are especially encouraged to apply.
The Opportunity:
You will have opportunities to productively collaborate with other researchers across departments, present your work to project teams, and contribute to scientific publications.
The successful candidate will be integral to the Pharmaceutical Development Department, collaborating with experts to advance the understanding of key considerations in formulation development and to elucidate the molecular mechanisms governing stability in therapeutic formulations using in silico methods.
You will be part of the Genentech post-doctoral training program and the Pharmaceutical Development Innovation Team offering an exceptional environment and the opportunity to pursue fundamental science questions within a context focused on drug development and breakthrough discoveries.
Elevate your research career to new heights with Genetech’s Postdoctoral Program! Join a prestigious community of early career scientists and kick-start your journey toward becoming a scientific leader in biotechnology and bioengineering. With competitive salaries and fully funded research expenses, you can dedicate yourself to groundbreaking research that aligns with Genentech strategic ambitions.
The postdoc program is designed to empower recent Ph.D. graduates to conduct world-class research, publish in top-tier journals, and build a robust scientific network. By joining us, you will receive the mentorship and support necessary to develop into an independent scientist and leader.
The Genentech Postdoc Program provides access to world-class seminars, professional development workshops, and networking opportunities. Apply now to Genentech Postdoctoral Program and unlock your full potential!

Requirements

• Ph.D. with a proven track record of excellence in computational biophysics and/or computational chemistry.
• Must have advanced at least one key research project as evidenced by a first author paper published or accepted in a leading peer-reviewed journal.
• Independent scientist with outstanding communication skills, a strong passion and commitment to science, who works well within a team
• Excited about supporting large molecule therapeutic development
• Hands-on experience in molecular dynamics simulations, particularly with antibodies and/or proteins is required.
• A proven track record of successfully developing in silico methods to provide mechanistic explanations for experimental observations is required.

Nice To Haves

• Experience with co-solvent MD, is highly desired.
• Working knowledge of basic machine learning is a plus.

Responsibilities

• productively collaborate with other researchers across departments
• present your work to project teams
• contribute to scientific publications
• collaborating with experts to advance the understanding of key considerations in formulation development and to elucidate the molecular mechanisms governing stability in therapeutic formulations using in silico methods
• conduct world-class research
• publish in top-tier journals
• build a robust scientific network

Benefits

• Relocation benefits are available for this job posting.
• competitive salaries
• fully funded research expenses

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees