POSTDOCTORAL ASSOCIATE

Duke Careers • Durham, NC

1d

About The Position

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Lee Lab Postdoctoral Associate – Radiation-induced tissue injury and regeneration

The Lee lab in the Department of Radiation Oncology at Duke University is seeking a highly motivated and independent scientist for a full-time Postdoctoral Associate position in the field of normal tissue injury from ionizing radiation exposure. This NIH-funded position will study acute and delayed injury of the intestines and oral mucosa induced by radiation, focusing on mechanisms of regenerative reprogramming and stromal-epithelial interactions. Complementary approaches will be used, including genetically engineered mouse models, histopathology, mouse and human organoids, CRISPR-Cas9 gene editing, single-cell sequencing, and spatial transcriptomics. A PhD, MD, MD/PhD, or equivalent degree in biomedical sciences-related fields and a track record of publications in peer-reviewed journals are required. Experience and expertise in analyzing single-cell sequencing data are preferred. This candidate must be detail-oriented and well-organized, with strong communication skills and the ability to work in a fast-paced, interactive team environment.

Requirements

• A PhD, MD, MD/PhD, or equivalent degree in biomedical sciences-related fields and a track record of publications in peer-reviewed journals are required.
• The Postdoctoral Appointee holds a PhD or equivalent doctorate (e.g.ScD, MD, DVM). Candidates with non-US degrees may be required to provide proof of degree equivalency.
• Conformance to standards of responsible conduct in research
• Compliance with good scholarly and research practice
• Maintenance of a laboratory notebook and/or other comparable records of research activity, which remains the property of Duke University upon termination
• Adherence to University standards regarding use of isotopes, chemicals, infectious agents, animals, human subjects, and the like
• Open and timely discussion with the mentor regarding all facets of the Postdoctoral Appointee's research activities.
• Prompt disclosure to the mentor regarding the possession and desire to distribute materials, reagents, software, copyrightable and potentially patentable discoveries derived from the Postdoctoral Appointee's research.
• Collegial conduct towards members of the research group and others as described in the Duke University School of Medicine Honor Code of Professional Conduct and other relevant conduct policies pertaining to other schools at Duke University.
• Compliance with all applicable University and departmental policies and procedures.

Nice To Haves

• Experience and expertise in analyzing single-cell sequencing data are preferred.
• This candidate must be detail-oriented and well-organized, with strong communication skills and the ability to work in a fast-paced, interactive team environment.

Responsibilities

• Perform various in vivo and in vitro experiments to dissect molecular and cellular mechanisms underlying acute epithelial injury and delayed fibrosis following high-dose radiation exposure.
• Assist with maintaining lab mouse colony: set up crosses, perform tail clip biopsies, mark mice (tattoo, ear tag, etc.), and wean pups
• Collect, analyze, manage, and interpret data and prepare reports
• Prepare manuscripts for publication in peer-reviewed journals
• Contribute to writing research grants and contracts
• Assist with managing IACUC, IRB, and IBC protocols as well as lab safety SOPs.
• Must be flexible to work on weekends or shifts

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree