Postdoctoral Associate

Rutgers University • Piscataway, NJ

15h

About The Position

Rutgers, the State University of New Jersey, is seeking a Postdoctoral Associate in the Center for Advanced Biotechnology and Medicine ( CABM ) of Rutgers Biomedical and Health Sciences ( RBHS ). Under the direction of the Principal Investigator, the Postdoctoral Associate will perform investigations on regulation of utilization of dietary fiber and host glycans by Hybrid Two-Component System ( HTCS ) transcription factors in Bacteroides . The research project will focus on structural characterization of B. thetaiotaomicron HTCS transcription factors; identification of ligands that bind to the extracellular domains of HTCS proteins; and investigations of the cellular localization of B. thetaiotaomicron HTCS proteins. The research will involve both cellular and in vitro studies. In addition to experimental research and contributions to maintaining the laboratory, the Postdoctoral Associate will be expected to prepare manuscripts for publication, present research at local and national meetings, and contribute to grant applications and reporting. The Postdoctoral Associate will collaborate effectively with other members of the laboratory and will have an opportunity to guide undergraduate researchers. Among the key duties of this position are the following: Performs experimental research on structural and functional characterization of Hybrid-Two-Component Systems (HTCSs) in Bacteroides. Uses molecular biology and molecular genetic techniques to engineer plasmids for expression of HTCS proteins. Develops expression systems and purification protocols for production of high-quality HTCS proteins and domain constructs for biochemical and structural analyses. Determines structures of HTCS proteins and/or domain constructs using appropriate methods such as X-ray crystallography and cryoEM. Overview New Jersey’s academic health center, Rutgers Biomedical and Health Sciences ( RBHS ) takes an integrated approach to educating students, providing clinical care, and conducting research, all with the goal of improving human health. Aligned with Rutgers University–New Brunswick and collaborating university wide, RBHS includes eight schools, a behavioral health network, and five centers and institutes that focus on cancer treatment and research, neuroscience, advanced biotechnology and medicine, environmental and occupational health, and health care policy and aging research. Our faculty are teachers, clinicians, and scientists with unparalleled experience who advance medical innovation and provide patient care informed by the latest research findings. We offer an outstanding education in medicine, dentistry, pharmacy, public health, nursing, biomedical research, and the full spectrum of allied health careers. Our clinical and academic facilities are located throughout the state—at Rutgers University–New Brunswick, including Piscataway; and at locations in Newark, Scotch Plains, Somerset, Stratford, and other locations. Clinical partners include Robert Wood Johnson University Hospital in New Brunswick, Newark’s University Hospital in Newark, and other affiliates. Through this community of healers, scientists, and scholars, Rutgers is equipped as never before to transform lives.

Nice To Haves

• Technical expertise in biochemistry, biphysics and molecular biology is preferred.
• Experience in microbiology, structural biology and/or transcriptomics is desirable.
• Experience with microbiology (cell culture and molecular genetics), transcriptomics, protein expression and purification and structural analysis are advantageous.

Responsibilities

• Performs experimental research on structural and functional characterization of Hybrid-Two-Component Systems (HTCSs) in Bacteroides.
• Uses molecular biology and molecular genetic techniques to engineer plasmids for expression of HTCS proteins.
• Develops expression systems and purification protocols for production of high-quality HTCS proteins and domain constructs for biochemical and structural analyses.
• Determines structures of HTCS proteins and/or domain constructs using appropriate methods such as X-ray crystallography and cryoEM.
• Prepare manuscripts for publication
• Present research at local and national meetings
• Contribute to grant applications and reporting
• Collaborate effectively with other members of the laboratory
• Guide undergraduate researchers

What This Job Offers

• Job Type: Full-time
• Education Level: No Education Listed