UNIV - Post Doctoral Scholar - Department of Pharmacology and Immunology

Medical University of South Carolina • Charleston, SC

13d

About The Position

Seeking an individual, preferably with microsurgical experience for a position in neuroimmunology for projects that encompasses basic and translational research. Work in the laboratory is centered around the complement system and neuroinflammatory mechanisms. Ongoing projects involve investigating acute and chronic neuroimmune responses occurring after stroke or after different types of traumatic brain injury, including the long-term neurodegenerative sequalae of injury. For this position, work will be focused on mouse models of stroke and traumatic brain injury the. Ideally, the candidate will have experience with the murine middle cerebral artery occlusion model, although training can be provided. Other aspects of the project will include high resolution and confocal microscopy, cellular and molecular immune profile analysis, therapeutic evaluation of drugs, and detailed assessments of motor and cognitive functions. The laboratory is also developing novel transgenic animals for mechanistic studies, and is involved in the development (and commercialization) of novel therapeutic approaches. Postdoctoral position Medical University of South Carolina, Charleston Department of Microbiology and Immunology Laboratory of Dr. Stephen Tomlinson

Requirements

• A PhD degree in biology or other natural, life or health care science related to the assigned area of research.
• For candidates with previous experience with the mouse middle cerebral artery occlusion model, a Batchelor’s degree is sufficient.
• Ability to perform job functions in an upright position.
• Ability to perform job functions in a seated position.
• Ability to perform job functions while walking/mobile.
• Ability to climb stairs.
• Ability to work indoors.
• Ability to work in all cold temperature extremes, i.e. spot coolers.
• Ability to bend at the waist.
• Ability to twist at the waist.
• Ability to perform 'pinching' operations.
• Ability to fully use both hands/arms.
• Ability to perform repetitive motions with hands/wrists/elbows and shoulders.
• Ability to fully use both legs.
• Ability to reach in all directions.
• Possess good finger dexterity.
• Ability to maintain tactile sensory functions.
• Ability to maintain good olfactory sensory function.
• Ability to lift and carry 15 lbs., unassisted.
• Ability to lift objects, up to 15 lbs., from floor level to height of 72 inches, unassisted.
• Ability to lower objects, up to 15 lbs., from height of 72 inches to floor level, unassisted.
• Ability to push/pull objects, up to 15 lbs., unassisted.
• Ability to lift and carry objects up to 15 lbs. a distance of five (5) floors and to outlying buildings.
• Ability to maintain 20/40 vision, corrected.
• Ability to see and recognize objects close at hand.
• Ability to see and recognize objects at a distance.
• Ability to match or discriminate between colors.
• Ability to determine distance/relationship between objects; depth perception.
• Good peripheral vision capabilities.
• Ability to maintain hearing acuity, with correction.
• Ability to perform gross motor functions with frequent fine motor movements.
• Ability to be qualified physically (by medical personnel) for respirator use, initially and annually.
• Ability to work alone in isolated areas, such as darkrooms.
• Ability to obtain and maintain a valid drivers license.
• Computer literacy.
• Ability to work rotating shifts as required.
• Ability to work overtime as required.
• Ability to learn and use new processes, tools and equipment as required.

Nice To Haves

• microsurgical experience
• experience with the murine middle cerebral artery occlusion model

Responsibilities

• Participate in a project related to above described work, including perform surgical procedures. Prepare sections from mouse brains and process for histology and immune-microscopy. Perform various microscopy techniques. Evaluate mice via various behavioral tasks. 35%
• In terms of the above listed areas of research, perform high dimensional analyses of post-injury immune landscape, analyze and interpret data. Will also involve use of image analysis software and generation of computer images. Determine behavioral outcomes in terms of pathophysiological findings. 35%
• Collaborate with other lab personnel in related projects. Participate in lab meetings and project-specific meetings with other lab personnel. 15%
• Keep records and up to date lab notebook/lab archives. Assist with writing manuscripts and grants. Keep up to date with relevant literature. 15%

What This Job Offers

• Job Type: Full-time
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees