Post Doctoral Fellow

Saint Louis University • St. Louis, MO

7d

About The Position

Saint Louis University’s Department of Neurology invites applications for a Postdoctoral Research Fellow to join our multidisciplinary team working on an NIH-funded project. The project investigates alcohol-induced cerebrovascular dysfunction, focusing on the role of lipid signaling in blood-brain barrier (BBB) disruption and neuroinflammation. The postdoctoral fellow will be involved in MCAO surgeries, biochemical analysis, and behavioral testing in a cutting-edge research environment. This position offers an opportunity to conduct innovative research on the effects of alcohol exposure on cerebrovascular health and neuroinflammation. For more information on my research background and publications, please visit my ORCID profile: https://orcid.org/0000-0002-7691-8948.

Requirements

• A PhD in Neuroscience, Neurobiology, or a related field.
• Experience in surgical techniques, specifically MCAO, for stroke models in mice.
• Strong background in biochemical assays, including Western blotting, PCR, and immunohistochemistry.
• Experience with behavioral analysis in mice.
• First-author publication history in peer-reviewed journals.
• Strong communication skills and ability to collaborate with a diverse team of researchers.

Nice To Haves

• Experience with lipid signaling, autotaxin, and LPP3 pathways in cerebrovascular research.
• Knowledge of animal models of neuroinflammation and ischemic stroke.
• Familiarity with neuroimaging techniques and data analysis tools (e.g., ImageJ, GraphPad Prism).

Responsibilities

• Perform Middle Cerebral Artery Occlusion (MCAO) surgeries to model ischemic stroke in mice.
• Conduct biochemical assays to analyze lipid signaling, enzyme expression, and oxidative stress markers in brain tissue.
• Perform Western blotting, PCR, immunohistochemistry, and fluorescence imaging.
• Coordinate and execute behavioral studies to assess cognitive and motor deficits, including Morris Water Maze (MWM), Novel Object Recognition (NOR), and Fear Conditioning Tests (FCT).
• Collaborate with laboratory team members on experimental design, data analysis, and manuscript preparation.
• Contribute to grant writing and publication of research findings in peer-reviewed journals.

What This Job Offers

• Job Type: Full-time
• Career Level: Entry Level
• Education Level: Ph.D. or professional degree