Post Doctoral Fellow – Gene Therapy and Vector Engineering

Emory UniversityAtlanta, GA
7dOnsite

About The Position

The Bishawi Lab is seeking a highly motivated Postdoctoral with experience in gene therapy to support a growing program focused on translational genetic engineering in organ transplantation and cardiovascular disease. The successful candidate will play a key role in developing and optimizing viral and non-viral gene delivery platforms for in vitro and in vivo applications. JOB DESCRIPTION: Helps design and conduct research within a specified field while receiving advanced training from a designated Principal Investigator to enhance professional skills and research independence needed for pursuit of a career. The specific area of research in which the trainee is mentored is determined by the department and laboratory of the Postdoc. Designs and evaluates experiments. Develops new ideas that promote current research. Prepares and publishes scientific manuscripts under the direction of the Principal Investigator. May be responsible for operation of specific equipment. May teach techniques to others, train, and supervise research staff. Positions are temporary appointments as a research trainee. The initial appointment is for one year, renewal expected if progress is satisfactory and funds are available. Appointments cannot exceed five years.

Requirements

  • A doctoral degree or equivalent (Ph.D., M.D., ScD., D.V.M., DDS etc) in an appropriate field.
  • Excellent scientific writing ability and strong oral communication skills.
  • The ability to work effectively and collegially with colleagues.

Nice To Haves

  • Ph.D. in Molecular Biology, Biomedical Engineering, Genetics, or a related field (or equivalent industry experience).
  • Strong hands-on experience in vector design and gene delivery systems (AAV, lentivirus, or LNP).
  • Demonstrated experience in molecular cloning, virus production, and in vivo delivery techniques.
  • Familiarity with murine models of disease is strongly preferred.
  • Excellent organizational and communication skills.
  • CRISPR/Cas9-based genome editing
  • CRISPR screens
  • Tissue-specific or inducible promoter systems

Responsibilities

  • Design and construct expression plasmids and genetic vectors (e.g., AAV, lentivirus, LNP).
  • Produce, purify, and characterize viral vectors for gene transfer.
  • Perform transduction and transfection studies in cell culture systems and animal models.
  • Develop and validate molecular assays (qPCR, RT-PCR, Western blotting, ELISA).
  • Maintain detailed lab notebooks, protocols, and data analysis pipelines.
  • Work collaboratively with other scientists, clinicians, and trainees in the lab.
  • Present findings in internal meetings, conferences, and manuscripts.
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