Post Doc (0) - Lawson Lab

University of Massachusetts Medical School • Worcester, MA

8d

About The Position

Postdoctoral Position, Lawson Lab, UMass Chan Medical School A postdoctoral position is available in the Lawson Lab at University of Massachusetts Chan Medical School, Department of Molecular, Cell, and Cancer Biology (lawsonlab.umassmed.edu). The Lawson Lab utilizes the zebrafish as a model system to study the development of the circulatory and lymphatic systems. Responsibilities Current projects focus on two areas: Developmental nature of vascular anomalies. Our goal is to determine how developmental defects associated with known mutations in humans result in defective vascular or lymphatic function. Studies include identifying relevant molecular targets, linking cellular mechanisms and defects to disease phenotypes, and small molecule screening to identify therapeutics. Understanding vascular mural cell development. We seek to dissect transcriptional regulatory networks required for pericyte development. We have identified several candidate transcription factors and current efforts focus on genetic analysis of these candidates to determine how they regulate pericyte specification. For all projects, we routinely develop and apply cutting-edge approaches, including conditional genetics, CRISPR-based gene editing, single cell molecular analyses, and in vivo time lapse.

Requirements

• The ideal candidate will have experience in molecular biology as documented through their publication record.
• Applicants must otherwise be highly motivated and technically accomplished as documented by exceptional publication record.

Nice To Haves

• Prior expertise in the application of genome editing in model systems is welcome and general experience with model organisms is preferred.

What This Job Offers

• Job Type: Full-time
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees