Post-Doc Research Associate

UNC-Chapel HillChapel Hill, NC
15d

About The Position

The Department of Pharmacology at the University of North Carolina at Chapel Hill invites applications for a post-doctoral research associate position in the UNC Proteomics Core Facility (proteomics.unc.edu). The post-doc will work collaboratively with the Director, other team members at the core facility and UNC researchers (faculty, post-docs, graduate students). The post-doc will contribute to a variety of ongoing and new projects in collaboration with UNC researchers involved in COVID , cancer and drug discovery research. Specific focus will be on developing and implementing methods for novel applications, and with general direction of a senior or principal researcher, lead components of a larger research project or program. Contributions will include meeting with collaborators to discuss projects, developing experimental design, wet-lab method development, sample preparation, LC-MS method development and analysis, thorough data analysis and writing reports. To establish internal partnerships with research colleague, actively develop external contacts and networks relevant to the project and for future funding opportunities.

Requirements

  • Experience in the field of mass spectrometry-based proteomics and on-kinome profiling is required.
  • Experience reviewing samples for proteomics analysis (in-solution/in-gel digestion, TMT labeling, PTM enrichment, peptide fractionation)
  • Experience with Proteome Discoverer software used to analyze proteomics data.
  • The aptitude to lead in a team environment and mentor co-workers.
  • The ability to analyze data independently, problem solve and work on multiple projects at the same time is required.
  • Research experience in the field of specialization with demonstrated knowledge of equipment, biochemical laboratory techniques and procedures, and methods of analysis.

Nice To Haves

  • Ability to operate LC-MS instruments specifically Thermo Fisher mass spectrometry instruments Thermo QExactive, Lumos) and in-depth proteomics data analysis (using MaxQuant, Perseus, Proteome Discoverer, R) is desired.
  • Experience in leading and overseeing research methods and techniques within the framework of the research program.

Responsibilities

  • Meeting with collaborators to discuss projects
  • Developing experimental design
  • Wet-lab method development
  • Sample preparation
  • LC-MS method development and analysis
  • Thorough data analysis
  • Writing reports
  • Actively develop external contacts and networks relevant to the project and for future funding opportunities
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